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Antiplasmodial activity of root extract and fractions of Croton zambesicus.
The in-vivo antimalarial activities of Uvaria chamae and Hippocratea africana
- J. Okokon, B. Ita, A. E. Udokpoh
- Medicine, BiologyAnnals of tropical medicine and parasitology
- 1 October 2006
Although the question of their toxicities has still to be fully addressed, it is clear that both U. chamae and H. africana possess considerable antimalarial activity and they, or drugs based on their antimalaria constituents, may prove useful in the treatment of human malaria.
Pharmacological screening and evaluation of antiplasmodial activity of Croton zambesicus against Plasmodium berghei berghei infection in mice
The extract demonstrated a dose-dependent chemosuppression or schizontocidal effect during early and in established infections, and also had repository activity that was lower than that of the standard drugs.
Antiplasmodial and antidiabetic activities of ethanolic leaf extract of Heinsia crinata.
The results suggest that the leaf extract of H. crinata possesses significant (P < .05) antiplasmodial as well as hypoglycemic and antidiabetic effects that can be employed in health care.
In vivo antimalarial activity of ethanolic leaf extract of Stachytarpheta cayennensis
The leaf extract possesses significant (P< 0.05) antiplasmodial activity which confirms it's use in folkloric medicine in the treatment of malaria.
Antiulcer and anticonvulsant activity of Croton zambesicus.
The ethanolic root extract of Croton zambesicus possesses antiulcer and anticonvulsant properties and significantly delayed the onset and latency of convulsion caused by PTZ and picrotoxin.
Hypoglycemic activity of aqueous leaf extract of Persea americana Mill
To evaluate the antidiabetic effects of Persea americana mill in alloxan-induced diabetic rats, fresh leaves of the tree plant were collected from the farm of the Faculty of Agriculture, University of Uyo, Nigeria and the extract was chemically tested for the presence of different chemical constituents using standard methods.
Antiinflammatory, analgesic and antipyretic activities of ethanolic root extract of Croton zambesicus.
The ethanolic root extract of C. zambesicus confirms its ethnomedical use in the treatment of malarial-associated symptoms and demonstrates a weak antiinflammatory activity.
Evaluation of antiplasmodial activity of ethanolic seed extract of Picralima nitida.
Antimalarial, antiplasmodial and analgesic activities of root extract of Alchornea laxiflora
- J. Okokon, Nkemnele Bensella Augustine, D. Mohanakrishnan
- MedicinePharmaceutical biology
- 1 January 2017
The results suggest that the root extract/fractions of A. laxiflora possess antimalarial, antiplasmodial and analgesic potentials and these justify its use in ethnomedicine to treat malaria and pain.