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21st century natural product research and drug development and traditional medicines.
The synergistic and reciprocal benefits of linking these 'omics technologies with robust ethnobotanical and ethnomedical studies of traditional medicines, to provide critically needed improved medicines and treatments that are inexpensive, accessible, safe and reliable are discussed. Expand
The antimicrobial activities of methanolic extracts of Eucalyptus camaldulensis and Terminalia catappa against some pathogenic microorganisms
The results obtained suggest that T. catappa and E. camaldulensis can be used in treating diseases caused by the test organisms. Expand
Antiinflammatory and Antimicrobial Activities of Mitracarpus scaber Extracts
Results from preliminary investigations on leaf extracts of Mitracarpus scaber establish its acclaimed potency as an antiinflammatory and antimicrobial agent and help to explain the rationale for the folkloric use of the plant in treating inflammatory disorders and microbial infections. Expand
Antioxidant and drug detoxification potentials of Hibiscus sabdariffa anthocyanin extract
- T. O. Ajiboye, N. Salawu, M. T. Yakubu, A. Oladiji, M. A. Akanji, J. Okogun
- Chemistry, Medicine
- Drug and chemical toxicology
- 12 February 2011
Hibiscus sabdariffa anthocyanin extract can act as a prophylactic by intervening as a free radical scavenger both in vitro and in vivo as well as inducing the phase II drug detoxification enzymes. Expand
Evaluation of in vitro antimycobacterial activity of Nigerian plants used for treatment of respiratory diseases
From the results of phytochemical analysis, terpenes and triterpenoid saponins are the most prominent compounds in these fractions and several reports earlier indicated that these metabolites are potential antimycobacterial agents. Expand
Preliminary organic geochemical studies of samples from the Niger delta (Nigeria) I. Analyses of crude oils for triterpanes
Abstract Crude-oil samples from three oilfields in the east and west of the Tertiary Niger delta, Nigeria, were analysed for pentacyclic triterpanes by gas chromatography and gas chromatography—mass… Expand
Antibacterial and antifungal compounds from Kigelia pinnata.
A biologically monitored fractionation of the methanolic extracts of the root and fruits of Kigelia pinnata D.C. led to the isolation of the naphthoquinones kigelinone (1), isopinnatal (2),… Expand
Hypoestoxide, a novel anti-inflammatory natural diterpene, inhibits the activity of IkappaB kinase.
It is demonstrated that hypoestoxide (HE) abrogates the production of pro-inflammatory cytokines (IL-1beta, IL-6, and TNF-alpha) in lipopolysaccharide (LPS)-activated normal human peripheral blood mononuclear cells and inhibition of nitric oxide by IL-1 beta- or IL-17-stimulated normal human chondrocytes. Expand
Antimycobacterial Friedelane-terpenoid from the Root Bark of Terminalia Avicennioides
Terminalia avicennioides is used to treat tuberculosis in the folk medicine of the Nupes of North Central Nigeria. Activity guided fractionation of the extract resulted in the isolation of… Expand
An ethnobotanical survey of indigenous flora for treating tuberculosis and other respiratory diseases in Niger State, Nigeria
An ethnobotanical survey of medicinal plants used locally for treating tuberculosis (TB) and other respiratory diseases was conducted from November 2004 to March 2005 in Niger State-Nigeria and a good number of plants identified have been reported to possess significant anti-tubercular activity. Expand