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Uniquely Hominid Features of Adult Human Astrocytes
It is reported here that protoplasmic astrocytes in human neocortex are 2.6-fold larger in diameter and extend 10-fold more GFAP (glial fibrillary acidic protein)-positive primary processes than their rodent counterparts, and it is posited that thisAstrocytic complexity has permitted the increased functional competence of the adult human brain. Expand
A brain-computer interface using electrocorticographic signals in humans.
It is demonstrated here for the first time that electrocorticographic (ECoG) activity recorded from the surface of the brain can enable users to control a one-dimensional computer cursor rapidly and accurately. Expand
Activation of the hippocampus in normal humans: a functional anatomical study of memory.
The results provide evidence for selective activation of the human hippocampal region in association with memory function and lead to a suggestion about the neural basis of repetition priming: following presentation of a stimulus, less neural activity is required to process the same stimulus. Expand
Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients.
There is a need for revision of the classical model of language localization, for it means that language cannot be reliably localized on anatomic criteria alone and a maximal resection with minimal risk of postoperative aphasia requires individual localization of language with a technique like stimulation mapping. Expand
Decoding two-dimensional movement trajectories using electrocorticographic signals in humans.
It is shown in humans that kinematic parameters can also be decoded from signals recorded by subdural electrodes on the cortical surface (ECoG) with an accuracy comparable to that achieved in monkey studies using intracortical microelectrodes. Expand
Spectral Changes in Cortical Surface Potentials during Motor Movement
Electrocorticographic signals associated with motor movement are quantified across 22 subjects with subdural electrode arrays placed for identification of seizure foci and sensorimotor representation was found to be somatotopic, localized in stereotactic space to rolandic cortex, and typically followed the classic homunculus with limited extrarolandic representation. Expand
Power-Law Scaling in the Brain Surface Electric Potential
A new paradigm of non-oscillatory “asynchronous,” scale-free, changes in cortical potentials, corresponding to changes in mean population-averaged firing rate, to complement the prevalent “synchronous” rhythm-based paradigm is suggested. Expand
Decoupling the Cortical Power Spectrum Reveals Real-Time Representation of Individual Finger Movements in Humans
In 10 human subjects performing a finger movement task, it is demonstrated that a principal component type of decomposition can naively separate low-frequency narrow-band rhythms from an asynchronous, broad-spectral, change at all frequencies between 5 and 200 Hz. Expand
A procedure for identifying regions preferentially activated by attention to semantic and phonological relations using functional magnetic resonance imaging
This method is notable in that a comparison of the two tasks within some of the individual subjects revealed activation patterns similar to the group average, especially within left inferior frontal and left superior/middle parietal cortices. Expand
Anatomic Localization and Quantitative Analysis of Gradient Refocused Echo-Planar fMRI Susceptibility Artifacts
Functional magnetic resonance imaging (fMRI) techniques, such as echo-planar imaging, can permit rapid, sensitive, whole-brain measurements of local blood flow-induced MR signal changes seen duringExpand