Empathy for Pain Involves the Affective but not Sensory Components of Pain
- T. Singer, B. Seymour, J. O’Doherty, H. Kaube, R. Dolan, C. Frith
- Psychology, BiologyScience
- 20 February 2004
Only that part of the pain network associated with its affective qualities, but not its sensory qualities, mediates empathy, suggesting that the neural substrate for empathic experience does not involve the entire "pain matrix".
Cortical substrates for exploratory decisions in humans
It is shown, in a gambling task, that human subjects' choices can be characterized by a computationally well-regarded strategy for addressing the explore/exploit dilemma, and a model of action selection under uncertainty that involves switching between exploratory and exploitative behavioural modes is suggested.
Dissociable Roles of Ventral and Dorsal Striatum in Instrumental Conditioning
- J. O’Doherty, P. Dayan, J. Schultz, R. Deichmann, Karl J. Friston, R. Dolan
- Psychology, BiologyScience
- 16 April 2004
This work scanned human participants with functional magnetic resonance imaging while they engaged in instrumental conditioning to suggest partly dissociable contributions of the ventral and dorsal striatum to the critic and the actor.
Empathic neural responses are modulated by the perceived fairness of others
It is shown that in men (at least) empathic responses are shaped by valuation of other people's social behaviour, such that they empathize with fair opponents while favouring the physical punishment of unfair opponents, a finding that echoes recent evidence for altruistic punishment.
Automatic and intentional brain responses during evaluation of trustworthiness of faces
The findings extend a proposed model of social cognition by highlighting a functional dissociation between automatic engagement of amygdala versus intentional engagement of STS in social judgment.
Abstract reward and punishment representations in the human orbitofrontal cortex
- J. O’Doherty, M. Kringelbach, E. Rolls, J. Hornak, C. Andrews
- Psychology, BiologyNature Neuroscience
Findings indicate that one emotional involvement of the human orbitofrontal cortex is its representation of the magnitudes of abstract rewards and punishments, such as receiving or losing money.
Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence.
Converging neuroimaging and clinical findings suggest that ACC function mediates context-driven modulation of bodily arousal states during effortful cognitive and motor behaviour.
Reward representations and reward-related learning in the human brain: insights from neuroimaging
- J. O’Doherty
- Psychology, BiologyCurrent Opinion in Neurobiology
- 1 December 2004
Human and Rodent Homologies in Action Control: Corticostriatal Determinants of Goal-Directed and Habitual Action
The neural basis of the integration of learning and motivation in choice and decision-making is still controversial and some recent hypotheses relating to this issue are reviewed.
Orbitofrontal Cortex Encodes Willingness to Pay in Everyday Economic Transactions
The neural basis of the WTP computation is investigated by scanning hungry subjects' brains using functional magnetic resonance imaging and it is found that activity in the medial orbitofrontal cortex and in the dorsolateral prefrontal cortex encodes subjects' WTP for the items.