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- Publications
- Influence
Engineering geological models: an introduction: IAEG commission 25
- S. Parry, F. J. Baynes, +5 authors D. Paul
- Engineering
- Bulletin of Engineering Geology and the…
- 18 February 2014
The generation and use of engineering geological models should be a fundamental activity for any geotechnical project. Such models are an essential tool for engineering quality control and provide a… Expand
Exploring Misogyny across the Manosphere in Reddit
- Tracie Farrell Frey, M. Fernández, J. Novotny, H. Alani
- Computer Science, Sociology
- WebSci
- 26 June 2019
TLDR
Rapid and simple preparation of thiol-ene emulsion-templated monoliths and their application as enzymatic microreactors.
- J. Lafleur, S. Senkbeil, +5 authors J. P. Kutter
- Chemistry, Medicine
- Lab on a chip
- 5 May 2015
A novel, rapid and simple method for the preparation of emulsion-templated monoliths in microfluidic channels based on thiol-ene chemistry is presented. The method allows monolith synthesis and… Expand
Dimethylamino Acid Esters as Biodegradable and Reversible Transdermal Permeation Enhancers: Effects of Linking Chain Length, Chirality and Polyfluorination
- J. Novotny, P. Kováříková, M. Novotný, B. Janůšová, A. Hrabálek, K. Vávrová
- Chemistry, Medicine
- Pharmaceutical Research
- 1 April 2009
PurposeSeries of N,N-dimethylamino acid esters was synthesized to study their transdermal permeation-enhancing potency, biodegradability and reversibility of action. Effects of chirality, linking… Expand
Transdermal and dermal delivery of adefovir: effects of pH and permeation enhancers.
- K. Vávrová, Kateřina Lorencová, J. Klimentova, J. Novotny, Antoni N Holý, A. Hrabálek
- Chemistry, Medicine
- European journal of pharmaceutics and…
- 1 June 2008
The objective of this work was to investigate feasibility of transdermal and dermal delivery of adefovir (9-(2-phosphonomethoxyethyl)adenine), a broad-spectrum antiviral from the class of acyclic… Expand
Fluid manipulation on the micro-scale: Basics of fluid behavior in microfluidics.
- J. Novotny, F. Foret
- Chemistry, Medicine
- Journal of separation science
- 2017
Fluid manipulation on the micro-scale (microfluidics) is bringing new potential applications in a number of fields, including chemistry, biology and medicine. At sub-millimeter channel scale, some… Expand
Permeation enhancer dodecyl 6-(dimethylamino)hexanoate increases transdermal and topical delivery of adefovir: influence of pH, ion-pairing and skin species.
- K. Vávrová, Kateřina Lorencová, J. Novotny, A. Holý, A. Hrabálek
- Chemistry, Medicine
- European journal of pharmaceutics and…
- 1 November 2008
Adefovir (9-(2-phosphonomethoxyethyl)adenine) is an acyclic nucleoside phosphonate currently used for the treatment of hepatitis B. The aim of this study was to evaluate the effect of permeation… Expand
Automatic generation of inter-passage links based on semantic similarity
- P. Knoth, J. Novotny, Z. Zdráhal
- Computer Science
- COLING
- 23 August 2010
TLDR
Bilirubin : chemistry, regulation and disorder
- J. Novotny, Florian Sedlacek
- Chemistry
- 2012
Preface Biophysical & Technical Aspects of Phototherapy for Neonatal Hyperbilirubinemia Genetic Variants in Bilirubin Metabolism Pathway, Serum Bilirubin & Cardiovascular Disease Molecular Simulation… Expand
- 4
Synthesis of fluorescent C24-ceramide: evidence for acyl chain length dependent differences in penetration of exogenous NBD-ceramides into human skin.
- J. Novotny, K. Pospěchová, A. Hrabálek, R. Čáp, K. Vávrová
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 15 December 2009
Topical skin lipid supplementation may provide opportunities for controlling ceramide (Cer) deficiency in skin diseases such as atopic dermatitis or psoriasis. Here we describe the synthesis of a… Expand