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Diphencyprone in the treatment of long‐standing alopecia areata
Diphencyprone is found to be an effective stimulator of hair growth in patients with severe and long‐standing alopecia areata and regrew hair on the treated side.
A double‐blind evaluation of topical isotretinoin 0.05%, benzoyl peroxide gel 5% and placebo in patients with acne
A double‐blind, randomized study comparing isotretinoin gel (Isotrex‐®), its vehicle base, and benzoyl peroxide was performed on 77 patients with mild to moderate acne vulgaris.
Utilization of epidermal phospholipase A2 inhibition to monitor topical steroid action
The effect of several steroid creams on epidermal phospholipase A2 activity in symptomless psoriatic and normal epidermis was studied and differential inhibition resulted in PLA2 activity approaching or attaining the normal range regardless of its initial level.
A single-blind comparison of topical erythromycin/zinc lotion and oral minocycline in the treatment of acne vulgaris
The erythromycin/zinc complex was more effective in reducing the numbers of comedones by 4 weeks and at 12 weeks and superficial inflamed lesions by 12 weeks.
Characterization and activity of phospholipase A2 in normal human epidermis and in lesion‐free epidermis of patients with psoriasis or eczema
It is suggested that the raised phospholipase A2 activity demonstrated in the lesion‐free epidermis of psoriasis may play an important role in the pathogenesis of the disease.
A histological and immunocytochemical study of early acne lesions
It is hypothesized that this early lymphocytic infiltrate in acne lesions represents a cell mediated immune response to an antigen within the duct lumen.
Isotretinoin--an explanation for its long-term benefit.
This study confirms earlier data, and that of the German multi-centres and Strauss et al (1), that the optimum dose schedule for treating acne patients is 1 mg/kg/day regime.
Vitilligo following diphencyprone dermatitis
Failure of treatment of familial widespread hidradenitis suppurativa with isotretinoin
The rationale for treating hidradenitis suppurativa with isotretinoin is called into question.
Alopecia areata treated with diphencyprone: is an allergic response necessary?
It would appear that the eliciting of an allergic reaction after application of DPC is an integral part of successful treatment resulting in hair growth.