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Role of platelet-derived growth factor in wound healing: synergistic effects with other growth factors.
Platelet-derived growth factor (PDGF) in vitro stimulates DNA synthesis and chemotaxis of fibroblasts and smooth muscle cells and stimulates collagen, glycosaminoglycan, and collagenase production byExpand
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[55] Chromatographic analysis of pteridines
Publisher Summary This chapter discusses the chromatographic analysis of pteridines. Pteridines are present in almost all types of biological tissues. Tetrahydrobiopterin is of interest to manyExpand
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Biopterin cofactor biosynthesis: independent regulation of GTP cyclohydrolase in adrenal medulla and cortex.
Guanosine triphosphate cyclohydrolase, the enzyme that is apparently rate-limiting in biopterin biosynthesis, is increased in adrenal cortex and medulla of rats treated with insulin or reserpine.Expand
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Effect of dietary ascorbic acid on the incidence of spontaneous mammary tumors in RIII mice.
A study of the effect of different amounts of L-ascorbic acid (vitamin C), between 0.076% and 8.3%, contained in the food has been carried out with ten groups of RIII mice (seven ascorbic acid andExpand
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Acellular vascular matrix: a natural endothelial cell substrate.
A preliminary assessment was made of the acellular vascular matrix graft as a substrate for endothelial cell seeding, with respect to surface pretreatment (none versus fibronectin and/or serum) andExpand
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Screening for biopterin defects in newborns with phenylketonuria and other hyperphenylalaninemias.
The newborn screening for phenylketonuria (PKU) has become a common practice in many countries. The success of this type of mass screening is the result of the reliability of the Guthrie test in theExpand
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739 TRANSIENT BIOPTERIN SYNTHETASE DEFICIENCY IN A NEW-BORN WITH PHENYLKETONURIA
Atypical forms of phenylketonuria (PKU) are associated with defects in the synthesis or regeneration of the biopterin cofactors. In order to prevent irreversible neurological damage, patients withExpand
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Novel esters and amides of nonsteroidal antiinflammatory carboxylic acids as antioxidants and antiproliferative agents.
A series of phenolic antioxidant ester and amide derivatives of the nonsteroidal antiinflammatory drug naproxen was designed to have both antiinflammatory and cytoprotective activity. Compounds wereExpand
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Acellular vascular matrix: A natural endothelial cell substrate
A preliminary assessment was made of the acellular vascular matrix graft as a substrate for endothelial cell seeding, with respect to surface pretreatment (none versus fibronectin and/or serum) andExpand
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Characterization of the In Vitro Anti-inflammatory Activity of AL-5898 and Related Benzopyranyl Esters and Amides
Selected ester- (AL-5898 and AL-8417) and amide-linked benzopyran analogues (AL-7538 and AL-12615) were evaluated in vitro for their ability to inhibit key enzymes/processes of the inflammatoryExpand
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