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Cyclic mechanical strain regulates the development of engineered smooth muscle tissue
We show that the appropriate combinations of mechanical stimuli and polymeric scaffolds can enhance the mechanical properties of engineered tissues. The mechanical properties of tissues engineeredExpand
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Impact of a group mind/body intervention on pregnancy rates in IVF patients.
OBJECTIVE To determine if women who were randomized to a mind/body program before starting their first IVF cycle would have higher pregnancy rates than control subjects. DESIGN Randomized,Expand
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Engineered smooth muscle tissues: regulating cell phenotype with the scaffold.
Culturing cells on three-dimensional, biodegradable scaffolds may create tissues suitable either for reconstructive surgery applications or as novel in vitro model systems. In this study, we haveExpand
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Smooth muscle cell adhesion to tissue engineering scaffolds.
Synthetic polyesters of lactic and glycolic acid, and the extracellular matrix molecule collagen are among the most widely-utilized scaffolding materials in tissue engineering. However, the mechanismExpand
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Mechanical stimulation and mitogen-activated protein kinase signaling independently regulate osteogenic differentiation and mineralization by calcifying vascular cells.
Ectopic calcification of vascular tissue is associated with several cardiovascular pathologies and likely involves active regulation by vascular smooth muscle cells and osteoblast-like vascularExpand
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Quantification of fibronectin adsorption to silicone-rubber cell culture substrates.
As the role of mechanical force in cellular signaling gained recognition, investigators designed a number of devices to deliver controlled regimens of mechanical force to cultured cells. One type ofExpand
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The growth and morphological behavior of salivary epithelial cells on matrix protein-coated biodegradable substrata.
The purpose of this study was to examine the growth and morphology of a salivary epithelial cell line (HSG) in vitro on several biodegradable substrata as an important step toward developing anExpand
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Elastic biodegradable poly(glycolide-co-caprolactone) scaffold for tissue engineering.
  • S. Lee, B. Kim, +8 authors Y. Kim
  • Materials Science, Medicine
  • Journal of biomedical materials research. Part A
  • 1 July 2003
Cyclic mechanical strain has been demonstrated to enhance the development and function of engineered smooth muscle (SM) tissues, and it would be necessary for the development of the elastic scaffoldsExpand
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Cyclic strain inhibits switching of smooth muscle cells to an osteoblast‐like phenotype
Ectopic calcification is commonly associated with cardiovascular disease, injury, aging, and biomaterial implantation. We hypothesized that the normal mechanical environment of smooth muscle cellsExpand
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Design Engineering of a Bioartificial Renal Tubule Cell Therapy Device
The use of a bioartificial renal tubule device composed of renal proximal tubule cells grown within a hollow fiber cartridge is a first step in engineering a bioartificial kidney to provide moreExpand
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