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Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis.
- A. Perner, N. Haase, +29 authors J. Wetterslev
- The New England journal of medicine
- 11 July 2012
BACKGROUND Hydroxyethyl starch (HES) [corrected] is widely used for fluid resuscitation in intensive care units (ICUs), but its safety and efficacy have not been established in patients with severe… Expand
Prediction of O-glycosylation of mammalian proteins: specificity patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase.
- J. Hansen, O. Lund, J. Engelbrecht, H. Bohr, J. Nielsen, J. Hansen
- Biology, Medicine
- The Biochemical journal
- 15 June 1995
The specificity of the enzyme(s) catalysing the covalent link between the hydroxyl side chains of serine or threonine and the sugar moiety N-acetylgalactosamine (GalNAc) is unknown. Pattern… Expand
[Postoperative nausea and vomiting].
During the last years huge amounts of literature have been reviewed systematically. Recently, guidelines have been proposed. For the first time a large prospective study has been performed on the… Expand
Resistance to V3-directed neutralization caused by an N-linked oligosaccharide depends on the quaternary structure of the HIV-1 envelope oligomer.
A conserved N-glycan present within the V3 loop of gp120 modulates the sensitivity to neutralization by antibodies directed to the V3 loop. A glycan-deficient mutant of HIVLAI, designated HIVA308,… Expand
Severe acquired immunodeficiency in European homosexual men.
Four previously healthy Danish homosexual men developed Kaposi's sarcoma or opportunistic infections with fever of unknown origin and lymphadenopathy. One patient died of a Pneumocystis carinii… Expand
Quantification of intracellular metabolic fluxes from fractional enrichment and 13C-13C coupling constraints on the isotopomer distribution in labeled biomass components.
- K. Schmidt, L. Norregaard, +4 authors J. Villadsen
- Chemistry, Medicine
- Metabolic engineering
- 1 April 1999
A method for the quantification of intracellular metabolic flux distributions from steady-state mass balance constraints and from the constraints posed by the measured 13C labeling state of biomass… Expand
Temporal relation of antigenaemia and loss of antibodies to core antigens to development of clinical disease in HIV infection.
- C. Pedersen, C. Nielsen, B. Vestergaard, J. Gerstoft, K. Krogsgaard, J. Nielsen
- Biology, Medicine
- British medical journal
- 5 September 1987
A total of 276 sequential serum samples from 34 men with antibodies to the human immunodeficiency virus (HIV) followed up for two to seven years were analysed for HIV antigen and antibodies to the… Expand
Survival differences in European patients with AIDS, 1979–89
Abstract Objectives : To examine the pattern of survival and factors associated with the outcome of disease in patients with AIDS. Design : Inception cohort. Data collected retrospectively from… Expand
Broadly neutralizing antibodies targeted to mucin-type carbohydrate epitopes of human immunodeficiency virus.
The cancer-related mucin-type carbohydrate neoantigen Tn was found on gp160 and gp120 of human immunodeficiency virus (HIV). Immunoglobulin G (IgG) and IgM monoclonal antibodies (MAbs) against Tn… Expand
Autologous HIV‐1 Neutralizing Antibodies: Emergence of Neutralization‐Resistant Escape Virus and Subsequent Development of Escape Virus Neutralizing Antibodies
- M. Arendrup, C. Nielsen, J. Hansen, C. Pedersen, L. Mathiesen, J. Nielsen
- Biology, Medicine
- Journal of acquired immune deficiency syndromes
- 1 March 1992
The capacity of consecutive human sera to neutralize sequentially obtained autologous virus isolates was studied. HIV-I was isolated three times over a 48–164-week period from three individuals… Expand