Anatomical landmarks of radical prostatecomy.
Prediction of Muscle-invasive Bladder Cancer Using Urinary Proteomics
Use of urinary peptides seems promising in estimating the probability a patient harbors muscle-invasive urothelial bladder cancer, and may also shed novel insights into the biology of bladder tumor progression not obtainable by other methods.
TGF-beta1 inhibits Cx43 expression and formation of functional syncytia in cultured smooth muscle cells from human detrusor.
Increased sensitivity to 4‐chloro‐m‐cresol and caffeine in primary myotubes from malignant hyperthermia susceptible individuals carrying the ryanodine receptor 1 Thr2206Met (C6617T) mutation
It is shown that myotubes derived from individuals carrying the RyR1 Thr2206Met (C6617T) mutation have an abnormal response of the intracellular calcium concentration to 4‐chloro‐m‐cresol and to caffeine.
Seminal Plasma as a Source of Prostate Cancer Peptide Biomarker Candidates for Detection of Indolent and Advanced Disease
Seminal plasma represents a robust source of potential peptide makers for primary PCa diagnosis and warrants further prospective validation to confirm the diagnostic potential of identified seminal biomarker candidates.
Alterations in connexin expression in the bladder of patients with urge symptoms
- J. Neuhaus, Friederike Pfeiffer, H. Wolburg, L. Horn, W. Dorschner
- Medicine, BiologyBJU International
- 1 September 2005
To compare the formation of gap junctions between detrusor smooth muscle cells in situ and the distribution of connexin (Cx)40, Cx43 and Cx45 expressions in bladder biopsies from a control group and from patients with urge symptoms, it is suggested that alterations of which may be involved in the causes of lower urinary tract symptoms are investigated.
Palmitate Induced IL-6 and MCP-1 Expression in Human Bladder Smooth Muscle Cells Provides a Link between Diabetes and Urinary Tract Infections
Induction of IL-6 in human bladder smooth muscle cells by fatty acids may represent a pathogenetic factor underlying the higher frequency and persistence of urinary tract infections in patients with metabolic diseases.
Acute focal bacterial nephritis is associated with invasive diagnostic procedures - a cohort of 138 cases extracted through a systematic review
The diagnosis of AFBN is set by characteristic clinico-radiological findings and differential diagnoses of this interstitial bacterial infection include renal abscess and tumor.
Individual receptor profiling as a novel tool to support diagnosis of bladder pain syndrome/interstitial cystitis (BPS/IC)
- J. Neuhaus, H. Schulte‐Baukloh, T. Schwalenberg
- Medicine, BiologyWorld journal of urology
- 1 October 2012
M2, P 2X1, P2X2 and H1 were significantly upregulated in BPS/IC patients, and H2 was occasionally highly overexpressed, implying posttranslational mechanisms being responsible for the altered receptor expressions.
Identification of Key Biomarkers in Bladder Cancer: Evidence from a Bioinformatics Analysis
The present study highlights an up to now unrecognized possible role of CASQ2 in cancer (BCa), and suggests that CRYAB may also be a candidate biomarker in BCa.