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Anti-epileptogenic effect of β-carotene and vitamin A in pentylenetetrazole-kindling model of epilepsy in mice
Vitamin A (Vit A) and its derivatives have recently been reported to be implicated in synaptic plasticity. In this study, the possible effect of Vit A and its precursor, beta-carotene on acuteExpand
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The characterization and quantification of antigen-induced Ca2+ oscillations in a rat basophilic leukaemia cell line (RBL-2H3).
Using the ratiometric Ca2+ indicator, indo-1, the antigen-induced increase in intracellular Ca2+ concentration ([Ca2+]i) was measured in individual RBL-2H3 cells which had been passively sensitizedExpand
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Inhibition of the antigen-induced activation of RBL-2H3 cells by cetiedil and some of its analogues.
Our previous studies on rat basophilic leukaemia (RBL-2H3) cells suggested that IK(Ca) channels similar to those in red blood cells (RBC) may be involved in the antigen-induced beta-hexosaminidaseExpand
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Inhibition of the antigen-induced activation of RBL-2H3 cells by charybdotoxin and cetiedil.
Quinidine and Ba(2+), non-selective K(+)-channel blockers, have previously been shown to inhibit antigen-induced mediator (beta-hexosaminidase) release from RBL-2H3 cells, a mucosal-type mast cellExpand
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Evaluation of immunotoxicity induced by propoxure in C57Bl/6 mice.
Insecticides are important candidates for immunotoxicology tests in order to assess the 'No Observable Adverse Effect Level' (NOAEL). Propoxure (PPX), as a carbamate household insecticide, has beenExpand
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Effect of cyclosporin and tacrolimus (FK506) on the antigen-induced mediator release, membrane potential and 86Rb+/K+ and Ca2+ fluxes in the RBL-2H3 cell line.
The immunosuppressants cyclosporin A (CsA) and tacrolimus (FK506) inhibit the activation by antigen of T-lymphocytes as well as mast cells. The mechanism of their action on mast cells has yet to beExpand
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The Effect of Chronic Administration of Silymarin on Contractile-Relaxation Response of Thoracic Aorta of Diabetic Rats
Abstract: Background and Aims: Diabetes mellitus is accompanied with higher incidence of cardiovascular disorders. There is some evidence on antidiabetic potential of silymarin. In this study theExpand
The effect of hesperetin on serum level of aspartate and alanine amoinotransferase and hepatic and cardiac level of malondialdehyde in diabetic rats
Background and Objective: Diabetes mellitus accompanies increased malondialdehyde as a marker of oxidative stress and increased serum level of aspartate and alanine aminotranferase due to tissueExpand