• Publications
  • Influence
Leptospirosis: a zoonotic disease of global importance.
In the past decade, leptospirosis has emerged as a globally important infectious disease. It occurs in urban environments of industrialised and developing countries, as well as in rural regionsExpand
  • 1,783
  • 177
  • PDF
Detection and quantification of leptospires in urine of dogs: a maintenance host for the zoonotic disease leptospirosis
Leptospirosis is a global zoonotic disease. Pathogenic Leptospira species, the causative agent of leptospirosis, colonize the renal tubules of chronically infected maintenance hosts such as dogs,Expand
  • 122
  • 12
Characterization of the Outer Membrane Proteome of Leptospira interrogans Expressed during Acute Lethal Infection
ABSTRACT Pathogenic Leptospira species adapt to a wide range of environmental conditions during disease transmission and infection. While the proteome of in vitro cultivated Leptospira has beenExpand
  • 129
  • 9
Molecular Analysis of the Enterobacter sakazakii O-Antigen Gene Locus
ABSTRACT Nucleotide polymorphism associated with the O-antigen-encoding locus, rfb, in Enterobacter sakazakii was determined by PCR-restriction fragment length polymorphism analysis. Based on theExpand
  • 73
  • 8
  • PDF
Cronobacter (Enterobacter sakazakii): an opportunistic foodborne pathogen.
Cronobacter spp. (Enterobacter sakazakii) are a recently described genus that is comprised of six genomospecies. The classification of these organisms was revised based on a detailed polyphasicExpand
  • 220
  • 6
Alveolar septal deposition of immunoglobulin and complement parallels pulmonary hemorrhage in a guinea pig model of severe pulmonary leptospirosis.
Human patients suffering from leptospirosis present with a diverse array of clinical manifestations, including the more severe and often fatal pulmonary form of the disease. The etiology of pulmonaryExpand
  • 176
  • 5
Purification and proteomic analysis of outer membrane vesicles from a clinical isolate of Leptospira interrogans serovar Copenhageni
The severe pulmonary form of leptospirosis (SPFL) is an especially serious and rapid disease process characterized by alveolar hemorrhage and acute respiratory failure. The outer membrane ofExpand
  • 89
  • 5
A Model System for Studying the Transcriptomic and Physiological Changes Associated with Mammalian Host-Adaptation by Leptospira interrogans Serovar Copenhageni
Leptospirosis, an emerging zoonotic disease with worldwide distribution, is caused by spirochetes belonging to the genus Leptospira. More than 500,000 cases of severe leptospirosis are reportedExpand
  • 67
  • 5
  • PDF
Temperature-Regulated Protein Synthesis by Leptospira interrogans
ABSTRACT Leptospira interrogans is an important mammalian pathogen. Transmission from an environmental source requires adaptations to a range of new environmental conditions in the organs and tissuesExpand
  • 72
  • 5
Host-Inducible Immunogenic Sphingomyelinase-Like Protein, Lk73.5, of Leptospira interrogans
ABSTRACT Leptospira interrogans causes a variety of clinical syndromes in animals and humans. Although much information has accumulated on the importance of leptospiral lipopolysaccharide inExpand
  • 49
  • 5
  • PDF