• Publications
  • Influence
A new look at cerebrospinal fluid circulation
According to the traditional understanding of cerebrospinal fluid (CSF) physiology, the majority of CSF is produced by the choroid plexus, circulates through the ventricles, the cisterns, and theExpand
  • 416
  • 21
  • PDF
Brain tissue oxygen monitoring in traumatic brain injury and major trauma: outcome analysis of a brain tissue oxygen-directed therapy.
OBJECT Cerebral ischemia is the leading cause of preventable death in cases of major trauma with severe traumatic brain injury (TBI). Intracranial pressure (ICP) control and cerebral perfusionExpand
  • 233
  • 9
Stimulation of the inflammatory system by reamed and unreamed nailing of femoral fractures. An analysis of the second hit.
It has been suggested that reamed intramedullary nailing of the femur should be avoided in some patients with multiple injuries. We have studied prospectively the effect of femoral reaming on theExpand
  • 143
  • 7
  • PDF
The role of pelvic floor denervation in the aetiology of idiopathic faecal incontinence
Weakness of the muscles of the pelvic floor and external anal sphincter may in theory be caused by a traction injury to the pelvic nerves incurred as a result of the excessive perineal descent thatExpand
  • 111
  • 7
TREATMENT OF ANISMUS IN INTRACTABLE CONSTIPATION WITH BOTULINUM A TOXIN
In seven patients with anismus the striated sphincter muscle complex was selectively weakened by local injection of Clostridium botulinum type A toxin. Symptom scores improved significantly andExpand
  • 190
  • 5
Valvular heart disease in patients taking pergolide.
OBJECTIVE To determine whether an association exists between pergolide and valvular heart disease. PATIENTS AND METHODS Three patients with severe, unexplained tricuspid regurgitation were examinedExpand
  • 169
  • 3
Pressure and prolapse--the cause of solitary rectal ulceration.
The cause of solitary rectal ulceration has been investigated using a method that radiologically visualises rectal voiding whilst simultaneously measuring intrarectal pressure and external analExpand
  • 99
  • 3
  • PDF
Blossoming contusions: identifying factors contributing to the expansion of traumatic intracerebral hemorrhage.
Here, the authors examined the factors involved in the volumetric progression of traumatic brain contusions. The variables significant in this progression are identified, and the expansion rate of aExpand
  • 22
  • 3
  • PDF
Prospective study of the effects of postanal repair in neurogenic faecal incontinence
The most important factor associated with a good result in the surgical treatment of neurogenic faecal incontinence by postanal repair is considered to be restoration of the obtuse anorectal angle.Expand
  • 120
  • 1
New method for the dynamic assessment of anorectal function in constipation
A new dynamic technique for the investigation of anorectal function has been developed. This involves radiological visualization of the rectum during voiding of a semisolid radio‐opaque contrastExpand
  • 125
  • 1
...
1
2
3
4
5
...