• Publications
  • Influence
Eicosanoids mediate nodulation reactions to bacterial infections in adults of the cricket, Gryllus assimilis.
TLDR
Findings in a hemimetabolous insect broaden the hypothesis that eicosanoids mediate cellular immune reactions to bacterial infections in most, if not all, insects.
Eicosanoids mediate microaggregation reactions to bacterial challenge in isolated insect hemocyte preparations.
TLDR
It is inferred that hemocytes are responsible for forming and secreting eicosanoids, which subsequently initiate nodulation by mediating hemocyte microaggregation in this system.
The influence of bacterial species and intensity of infections on nodule formation in insects.
TLDR
The nodulation reaction to bacterial infection occurs in all larval stages of M. sexta, and in older larvae of the tobacco hornworm and tenebrionid beetle, eicosanoids are involved in one or more steps in the overall process, and treating these insects with inhibitors of eicOSanoid biosynthesis prior toacterial infection severely impairs their ability to form nodules.
Calsenilin Is a Substrate for Caspase-3 That Preferentially Interacts with the Familial Alzheimer's Disease-associated C-terminal Fragment of Presenilin 2*
TLDR
It is found that calsenilin has the ability to interact with endogenous 25-kDa C-terminal fragment (CTF) that is a product of regulated endoproteolytic cleavage of PS2 and that the presence of the N141I PS2 mutation does not significantly alter the interaction of calsanilin with PS2.
Biochemical and immunocytochemical characterization of calsenilin in mouse brain
TLDR
The biochemical and immunohistochemical characterization of calsenilin, a novel calcium binding protein that has previously been shown to interact with presenilins 1 and 2, in mouse brain is described and it is established that calsanilin and presenILin 1 can interact at physiologic levels, and that calenil in is a developmentally regulated protein that is expressed primarily in the cerebellum and hippocampus.
Phosphorylation of calsenilin at Ser63 regulates its cleavage by caspase-3
TLDR
It is demonstrated that calsenilin can be phosphorylated by casein kinase I and that its phosphorylation can be regulated by intracellular calcium.
Eicosanoids mediate microaggregation and nodulation responses to bacterial infections in black cutworms, Agrotis ipsilon, and true armyworms, Pseudaletia unipuncta.
TLDR
The hypothesis that eicosanoids mediate cellular immune reactions in insects is supported, asFat body preparations were competent to biosynthesize prostaglandins, of which PGE(2) was the major product.
Eicosanoids mediate nodulation reactions to bacterial infections in adults of two 17-year periodical cicadas, Magicicada septendecim and M. cassini.
TLDR
Treating adults of the 17-year periodical cicadas, Magicicada septendecim and M. cassini, with eicosanoid biosynthesis inhibitors immediately prior to intrahemocoelic injections of the bacterium, Serratia marcescens, sharply reduced the nodulation response to bacterial challenges, broadening the hypothesis that eICosanoids mediate cellular immune reactions to bacterial infections in most, if not all, insects.
Eicosanoids mediate nodulation reactions to bacterial infections in larvae of the butterfly, Colias eurytheme.
TLDR
The hypothesis that eicosanoids mediate cellular immune responses to bacterial infections in these butterfly larvae, and more broadly, in most, if not all, insects, is supported.
Intracellular bacteria in blood smears in patients with central venous catheters.
TLDR
It is recommended that central venous catheters be removed in asymptomatic patients from a tertiary care university hospital in whom intracellular bacteria were found incidentally on routine manual differential cell counts of 100 white blood cells during a 12-month period.
...
1
2
...