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Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica.
From the ethyl acetate extract of the stem bark of Erythrina abyssinica, a new chalcone, 2',3,4,4'-tetrahydroxy-5-prenylchalcone (trivial name 5- prenylbutein) and a new flavanone along with known flavonoids have been isolated as the anti-plasmodial principles. Expand
Odor Composition of Preferred (Buffalo and Ox) and Nonpreferred (Waterbuck) Hosts of Some Savanna Tsetse Flies
- N. K. Gikonyo, A. Hassanali, P. G. Njagi, P. Gitu, J. Midiwo
- Biology, Medicine
- Journal of Chemical Ecology
- 1 May 2002
Electroantennogram-active compounds in odors from waterbuck were compared with those of two preferred hosts of tsetse flies, buffalo, Syncerus caffer, and ox, Bos indicus to suggest certain waterbuck-specific EAG-active components constitute a candidate allomonal blend in waterbuck odor. Expand
Anti-plasmodial activities and X-ray crystal structures of rotenoids from Millettia usaramensis subspecies usaramensis.
The dichloromethane extract of the stem bark of Millettia usaramensis subspecies usaramensis showed anti-plasmodial activity against the chloroquine sensitive (D6) and chloroquine resistant (W2)… Expand
Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti.
- A. Yenesew, S. Derese, J. Midiwo, M. Heydenreich, M. Peter
- Biology, Medicine
- Pest management science
- 1 October 2003
Saturation at the B/C ring junction and the presence of methoxy groups at C-2 and/or C-3 in deguelin and tephrosin appear to be important for the observed larvicidal activity. Expand
Phytochemical, Antimicrobial and Antiplasmodial Investigations of Terminalia brownii
- F. Machumi, J. Midiwo, +5 authors I. Muhammad
- Chemistry, Medicine
- Natural product communications
- 1 June 2013
Phytochemical investigation of the ethyl acetate-soluble fraction of stem bark extract of an African medicinal plant Terminalia brownii led to the isolation of a new oleanane-type triterpenoid, along… Expand
New ent-Clerodane and Abietane Diterpenoids from the Roots of Kenyan Croton megalocarpoides Friis & M. G. Gilbert.
The roots of the endangered medicinal plant Croton megalocarpoides collected in Kenya were investigated and twenty-two compounds isolated, which contained twelve new ent-clerodane and a new abietane diterpenoids and were evaluated against a series of microorganisms and against Plasmodium falciparum, however no activity was observed. Expand
The first 9-hydroxyhomoisoflavanone, and antiplasmodial chalcones, from the aerial exudates of Polygonum senegalense
Phytochemical re-examination of the aerial exudates of Polygonum senegalense forma senegalense has resulted in the isolation and characterization of a novel homoisoflavonoid, 5,7-… Expand
Rotenoids, isoflavones and chalcones from the stem bark of Millettia usaramensis subspecies usaramensis
From the stem bark of Millettia usaramensis subsp. usaramensis four new 12a-hydroxyrotenoids with the unusual trans B/C ring junction ((+)-12a-epimillettosin, (+)-usararotenoid-A,… Expand
Antiplasmodial flavonoids from Erythrina sacleuxii.
Chromatographic separation of the acetone extract of the root bark afforded a new is oflavone, 7-hydroxy-4'-methoxy-3'-prenylisoflavone (trivial name 5-deoxy-2'-3'- prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Expand
Isolation and characterization of an antifungal compound 5-hydroxy-7,4’-dimethoxyflavone from Combretum zeyheri
- Rumbidzai Mangoyi, J. Midiwo, S. Mukanganyama
- Biology, Medicine
- BMC Complementary and Alternative Medicine
- 14 November 2015
The compound 5-hydroxy-7,4’-dimethoxyflavone may be partly responsible for the reported antifungal activity of C. zeyheri, and may serve as a potential source of lead compounds that can be developed as antifundal phytomedicines. Expand