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Subjective and hormonal effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans
TLDR
Correlations between cortisol and DHEA levels and some physiological and psychological effects are consistent with animal data suggesting that hormones modulate some responses to drugs of abuse.
Human Pharmacology of the methamphetamine stereoisomers
Methamphetamine and ethanol interactions in humans
Cardiovascular Effects of 3,4-Methylenedioxymethamphetamine: A Double-Blind, Placebo-Controlled Trial
TLDR
The acute cardiovascular effects of oral MDMA are measured to compare these effects with those of a well-characterized cardiostimulant, the -agonist dobutamine to improve prediction of and intervention in cases of MDMA cardiotoxicity.
Stereoselectivity in the human metabolism of methamphetamine.
TLDR
The metabolism of MA is enantioselective, with formation of AMP having the highest isomer selectivity and the formation of pOH-MA was less affected by the MA enantiomer administered, suggesting that urine p OH-MA may be a more stable biomarker of MA metabolism.
Bioavailability of Sublingual Buprenorphine
TLDR
Sublingual exposure times between 3 and 5 minutes produce equivalent results, and study results indicate that bioavailability of sublingual buprenorphine is approximately 30%.
Buprenorphine Pharmacokinetics: Relative Bioavailability of Sublingual Tablet and Liquid Formulations
TLDR
The bioavailability of buprenorphine from a tablet to that from a reference solution was approximately 50% that from the liquid and was not affected by saliva pH, suggesting lower bioavailability from the tablet may be due to slow dissolution.
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