Author pages are created from data sourced from our academic publisher partnerships and public sources.
Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers.
Germline alterations of BRCA1 result in susceptibility to breast and ovarian cancer. The protein encoded by BRCA1 interacts in vivo with the BRCA1-associated RING domain (BARD1) protein. Accordingly,… Expand
Role of the endothelium in inflammatory bowel diseases.
- W. Cromer, J. Mathis, D. Granger, G. V. Chaitanya, J. Alexander
- World journal of gastroenterology
- 7 February 2011
Inflammatory bowel diseases (IBD) are a complex group of diseases involving alterations in mucosal immunity and gastrointestinal physiology during both initiation and progressive phases of the… Expand
HIV antiretroviral drug combination induces endothelial mitochondrial dysfunction and reactive oxygen species production, but not apoptosis.
- B. Jiang, Valeria Y. Hebert, Y. Li, J. Mathis, J. S. Alexander, T. Dugas
- Chemistry, Medicine
- Toxicology and applied pharmacology
- 1 October 2007
Numerous reports now indicate that HIV patients administered long-term antiretroviral therapy (ART) are at a greater risk for developing cardiovascular diseases. Endothelial dysfunction is an… Expand
Elevated levels of chemokine receptor CXCR4 in HER-2 negative breast cancer specimens predict recurrence.
INTRODUCTION CXCR4 is a chemokine receptor that has recently been implicated to play a pivotal role in breast cancer growth and metastasis. In animal models, reduction of CXCR4 expression… Expand
Genetic instability in human ovarian cancer cell lines.
- K. Orth, J. Hung, A. Gazdar, A. Bowcock, J. Mathis, J. Sambrook
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 27 September 1994
We have analyzed the stability of microsatellites in cell lines derived from human ovarian cancers and found that 5 out of 10 of the ovarian tumor cell lines are genetically unstable at the majority… Expand
Mesenchymal Stem Cells Effectively Deliver an Oncolytic Adenovirus to Intracranial Glioma
- A. Sonabend, I. Ulasov, M. Tyler, A. Rivera, J. Mathis, M. Lesniak
- Biology, Medicine
- Stem cells
- 1 March 2008
Gene therapy represents a promising treatment alternative for patients with malignant gliomas. Nevertheless, in the setting of these highly infiltrative tumors, transgene delivery remains a… Expand
Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma
- M. Stoff-Khalili, A. Rivera, +15 authors D. Curiel
- Breast Cancer Research and Treatment
- 13 January 2007
PurposeAlternative and complementary therapeutic strategies need to be developed for metastatic breast cancer. Virotherapy is a novel therapeutic approach for the treatment of cancer in which the… Expand
Transformation of human granulosa cells with the E6 and E7 regions of human papillomavirus.
- W. Rainey, C. Sawetawan, +5 authors B. Carr
- Biology, Medicine
- The Journal of clinical endocrinology and…
- 1 March 1994
Ovarian granulosa cells are the primary site of estrogen and progesterone synthesis and play an essential role in the maturation of the developing ovum. Freshly isolated granulosa cells are often… Expand
Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds
- A. Stoff, A. A. Rivera, +12 authors D. Curiel
- Medicine, Biology
- Journal of Molecular Medicine
- 12 January 2007
Fibromodulin, a member of the small leucine-rich proteoglycan family, has been recently suggested as a biologically significant mediator of fetal scarless repair. To assess the role of fibromodulin… Expand
Oncolytic adenoviruses – selective retargeting to tumor cells
Virotherapy is an approach for the treatment of cancer, in which the replicating virus itself is the anticancer agent. Virotherapy exploits the lytic property of virus replication to kill tumor… Expand