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Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessment
Abstract. For an understanding of the aberrant biology seen in mouse mutations and identification of more subtle phenotype variation, there is a need for a full clinical and pathologicalExpand
Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity.
Antibodies to ubiquitin have been used to search for evidence of abnormal protein degradation in amyotrophic lateral sclerosis--motor neuron disease (ALS). Anterior horn cell ubiquitin-immunoreactiveExpand
Renal ageing
The function of the kidney, as well as its morphology, changes markedly with age. The glomerular filtration rate falls progressively, independent of overt pathology. Glomerular, vascular andExpand
Deranged smooth muscle α-actin as a biomarker of intestinal pseudo-obstruction: a controlled multinational case series
Background and aims: Chronic idiopathic intestinal pseudo-obstruction (CIIP) is a severe motility disorder associated with significant morbidity. Several histopathological (neuropathic and myopathic)Expand
Olfactory Disorder in Motor Neuron Disease
In Parkinson's disease and Alzheimer's disease there is profound disorder of olfaction. The extent to which this modality is involved in motor neuron disease (MND) has been studied little. To addressExpand
Addition of Casein or Whey Protein to Colostrum or a Colostrum Supplement Product on Absorption of IgG in Neonatal Calves
Abstract The effects of the addition of nonimmunoglobulin protein on absorption of immunoglobulin G (IgG) from colostrum or colostrum supplement products were determined in two experiments. InExpand
Morphological and morphometric characterisation of Onuf's nucleus in the spinal cord in man
In the absence of a systematic morphometric study of Onuf's nucleus in man, this investigation defines the limits of variation of segmental position and the range of length and volume of Onuf'sExpand
Full-thickness biopsy findings in chronic intestinal pseudo-obstruction and enteric dysmotility
Background and Aims: Small bowel manometry is increasingly used in the clinical investigation of patients with symptoms of intestinal motor dysfunction. Enteric dysmotility (ED) has been suggested asExpand
Prediction of progression in pTa and pT1 bladder carcinomas with p53, p16 and pRb
Currently available prognostic tools appear unable to adequately predict recurrence and progression in non muscle-invasive bladder carcinomas. We aimed to assess the prognostic value ofExpand