• Publications
  • Influence
E‐cadherin regulates cell movements and tissue formation in early zebrafish embryos
  • S. G. Babb, J. Marrs
  • Biology, Medicine
  • Developmental dynamics : an official publication…
  • 1 June 2004
E‐cadherin is maternally expressed in most vertebrate species, but its function during early development of the vertebrate embryo proper is unknown. To directly examine E‐cadherin gene (cdh1)Expand
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Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex.
The cadherin-catenin complex is important for mediating homotypic, calcium-dependent cell-cell interactions in diverse tissue types. Although proteins of this complex have been identified, little isExpand
  • 339
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  • Open Access
Distinguishing roles of the membrane-cytoskeleton and cadherin mediated cell-cell adhesion in generating different Na+,K(+)-ATPase distributions in polarized epithelia
In simple epithelia, the distribution of ion transporting proteins between the apical or basal-lateral domains of the plasma membrane is important for determining directions of vectorial ionExpand
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  • Open Access
Myosin II Light Chain Phosphorylation Regulates Membrane Localization and Apoptotic Signaling of Tumor Necrosis Factor Receptor-1*
Activation of myosin II by myosin light chain kinase (MLCK) produces the force for many cellular processes including muscle contraction, mitosis, migration, and other cellular shape changes. TheExpand
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Zebrafish fetal alcohol syndrome model: effects of ethanol are rescued by retinoic acid supplement.
This study was designed to develop a zebrafish experimental model to examine defects in retinoic acid (RA) signaling caused by embryonic ethanol exposure. RA deficiency may be a causative factorExpand
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Zebrafish R‐cadherin (Cdh4) controls visual system development and differentiation
In zebrafish, R‐cadherin (cadherin‐4 or Cdh4) is expressed in the retina and in retinorecipient brain regions, suggesting that Cdh4 functions during visual system development. Cdh4 function wasExpand
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Cadherin‐2 function in the cranial ganglia and lateral line system of developing zebrafish
Cadherins are cell surface molecules that mediate cell–cell adhesion through homophilic interactions. Cadherin‐2 (also called N‐cadherin), a member of classic cadherin subfamily, has been shown toExpand
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Cadherin cell adhesion molecules in differentiation and embryogenesis.
The cadherin gene superfamily of calcium-dependent cell-cell adhesion molecules contains more than 40 members. We summarize functions attributed to these proteins, especially their roles in cellularExpand
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Gα12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton
Epiboly spreads and thins the blastoderm over the yolk cell during zebrafish gastrulation, and involves coordinated movements of several cell layers. Although recent studies have begun to elucidateExpand
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  • Open Access
Inhibiting cadherin function by dominant mutant E-cadherin expression increases the extent of tight junction assembly.
Previous studies have shown that induction of cadherin-mediated cell-cell adhesion leads to tight junction formation, and that blocking cadherin-mediated cell-cell adhesion inhibits tight junctionExpand
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  • Open Access