Contact allergenic potency: correlation of human and local lymph node assay data.
The present investigations show that the LLNA can be used to provide quantitative estimates of relative skin sensitizing potency EC(3) values that correlate closely with NOELs established from human repeat patch testing and from the clinical experience.
North American Contact Dermatitis Group Patch Test Results: 2015–2016
The results confirm that the epidemic of sensitivity to methylisothiazolinone has continued in North America and that patch testing with allergens beyond a screening tray is necessary for a complete evaluation of occupational and nonoccupational ACD.
Final Report of the Safety Assessment of Methylisothiazolinone
- Christina L. Burnett, W. Bergfeld, F. A. Andersen
- ChemistryInternational journal of toxicology
- 1 May 2010
The Cosmetic Ingredient Review Expert Panel concluded that there is a threshold dose response and that cosmetic products formulated to contain concentrations of MIT at 100 ppm (0.01%) or less would not be expected to pose a sensitization risk.
Contact allergy in children referred for patch testing: North American Contact Dermatitis Group data, 2001-2004.
Opinion is that adults and children in this group are equally likely to have allergic contact dermatitis; frequency of relevant allergen reactions differs.
North American Contact Dermatitis Group patch-test results, 1998 to 2000.
The findings reinforce the need for a more comprehensive group of diagnostic allergens than is found in the T.R.E.U. TEST, which is sold in the United States.
North American Contact Dermatitis Group patch test results for the detection of delayed-type hypersensitivity to topical allergens.
Fragrance contact dermatitis - a worldwide multicenter investigation (Part III).
This study evaluated the frequency of responses to selected fragrance materials in patients who were fragrance sensitive in eight centres worldwide with a fragrance mixture (FM) and 17 less well-studied fragrance materials.
North American Contact Dermatitis Group Patch Test Results 2013–2014
The NACDG patch testing results confirm that the epidemic of sensitivity to methylisothiazolinone previously documented in Europe is also occurring in North America.
North American Contact Dermatitis Group patch-test results, 1996-1998.
North American Contact Dermatitis Group Patch Test Results: 2011–2012
The NACDG patch-testing results document the beginning of the epidemic of sensitivity to methylisothiazolinones in North America, which has been well documented in Europe.