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Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends
The fields of tissue engineering and regenerative medicine aim at promoting the regeneration of tissues or replacing failing or malfunctioning organs, by means of combining a scaffold/supportExpand
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Natural polymers for the microencapsulation of cells
The encapsulation of living mammalian cells within a semi-permeable hydrogel matrix is an attractive procedure for many biomedical and biotechnological applications, such as xenotransplantation,Expand
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The dynamic effect of pipe-wall viscoelasticity in hydraulic transients. Part II—model development, calibration and verification
A state-of-the-art mathematical model has been developed to calculate hydraulic transients in pressurized polyethylene (PE) pipe systems. This hydraulic transient solver (HTS) incorporates additionalExpand
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Properties of melt processed chitosan and aliphatic polyester blends
Abstract Chitosan was melt blended with poly-ɛ-caprolactone (PCL), poly(butylene succinate) (PBS), poly(lactic acid) (PLA), poly(butylene terephthalate adipate) (PBTA), and poly(butylene succinateExpand
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Thermal properties of thermoplastic starch/synthetic polymer blends with potential biomedical applicability
Previous studies shown that thermoplastic blends of corn starch with some biodegradable synthetic polymers (poly(ε-caprolactone), cellulose acetate, poly(lactic acid) and ethylene-vinyl alcoholExpand
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Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments
The present review paper examines the use of different types of polymeric matrix composites in hard tissue replacement applications.The review presents the actual state of the art in the fields ofExpand
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Osteochondral defects: present situation and tissue engineering approaches
  • J. Mano, R. Reis
  • Medicine
  • Journal of tissue engineering and regenerative…
  • 1 July 2007
Articular cartilage is often damaged due to trauma or degenerative diseases, resulting in severe pain and disability. Most clinical approaches have been shown to have limited capacity to treatExpand
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Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications.
  • N. M. Alves, J. Mano
  • Chemistry, Medicine
  • International journal of biological…
  • 1 December 2008
Chitosan is a natural based polymer, obtained by alkaline deacetylation of chitin, which presents excellent biological properties such as biodegradability and immunological, antibacterial andExpand
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Three-dimensional plotted scaffolds with controlled pore size gradients: Effect of scaffold geometry on mechanical performance and cell seeding efficiency.
Scaffolds produced by rapid prototyping (RP) techniques have proved their value for tissue engineering applications, due to their ability to produce predetermined forms and structures featuring fullyExpand
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Smart thermoresponsive coatings and surfaces for tissue engineering: switching cell-material boundaries.
The smart thermoresponsive coatings and surfaces that have been explicitly designed for cell culture are mostly based on poly(N-isopropylacrylamide) (PNIPAAm). This polymer is characterized by aExpand
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