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- Publications
- Influence
Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends
- J. Mano, G. A. Silva, +9 authors R. Reis
- Materials Science, Medicine
- Journal of The Royal Society Interface
- 22 December 2007
The fields of tissue engineering and regenerative medicine aim at promoting the regeneration of tissues or replacing failing or malfunctioning organs, by means of combining a scaffold/support… Expand
Natural polymers for the microencapsulation of cells
- L. Gasperini, J. Mano, R. Reis
- Chemistry, Medicine
- Journal of The Royal Society Interface
- 6 November 2014
The encapsulation of living mammalian cells within a semi-permeable hydrogel matrix is an attractive procedure for many biomedical and biotechnological applications, such as xenotransplantation,… Expand
The dynamic effect of pipe-wall viscoelasticity in hydraulic transients. Part II—model development, calibration and verification
- D. Covas, I. Stoianov, J. Mano, H. Ramos, N. Graham, C. Maksimovic
- Physics, Engineering
- 1 January 2005
A state-of-the-art mathematical model has been developed to calculate hydraulic transients in pressurized polyethylene (PE) pipe systems. This hydraulic transient solver (HTS) incorporates additional… Expand
Properties of melt processed chitosan and aliphatic polyester blends
- V. Correlo, L. Boesel, M. Bhattacharya, J. Mano, N. Neves, R. Reis
- Materials Science
- 25 August 2005
Abstract Chitosan was melt blended with poly-ɛ-caprolactone (PCL), poly(butylene succinate) (PBS), poly(lactic acid) (PLA), poly(butylene terephthalate adipate) (PBTA), and poly(butylene succinate… Expand
Thermal properties of thermoplastic starch/synthetic polymer blends with potential biomedical applicability
- J. Mano, D. Koniarova, R. Reis
- Materials Science, Medicine
- Journal of materials science. Materials in…
- 1 February 2003
Previous studies shown that thermoplastic blends of corn starch with some biodegradable synthetic polymers (poly(ε-caprolactone), cellulose acetate, poly(lactic acid) and ethylene-vinyl alcohol… Expand
Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement: state of the art and recent developments
- J. Mano, R. A. Sousa, L. Boesel, N. Neves, R. Reis
- Materials Science
- 1 May 2004
The present review paper examines the use of different types of polymeric matrix composites in hard tissue replacement applications.The review presents the actual state of the art in the fields of… Expand
Osteochondral defects: present situation and tissue engineering approaches
Articular cartilage is often damaged due to trauma or degenerative diseases, resulting in severe pain and disability. Most clinical approaches have been shown to have limited capacity to treat… Expand
Chitosan derivatives obtained by chemical modifications for biomedical and environmental applications.
- N. M. Alves, J. Mano
- Chemistry, Medicine
- International journal of biological…
- 1 December 2008
Chitosan is a natural based polymer, obtained by alkaline deacetylation of chitin, which presents excellent biological properties such as biodegradability and immunological, antibacterial and… Expand
Three-dimensional plotted scaffolds with controlled pore size gradients: Effect of scaffold geometry on mechanical performance and cell seeding efficiency.
- J. Sobral, S. Caridade, R. A. Sousa, J. Mano, R. Reis
- Materials Science, Medicine
- Acta biomaterialia
- 1 March 2011
Scaffolds produced by rapid prototyping (RP) techniques have proved their value for tissue engineering applications, due to their ability to produce predetermined forms and structures featuring fully… Expand
Smart thermoresponsive coatings and surfaces for tissue engineering: switching cell-material boundaries.
- Ricardo M. P. da Silva, J. Mano, R. Reis
- Materials Science, Medicine
- Trends in biotechnology
- 1 December 2007
The smart thermoresponsive coatings and surfaces that have been explicitly designed for cell culture are mostly based on poly(N-isopropylacrylamide) (PNIPAAm). This polymer is characterized by a… Expand
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