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BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
Engulfment and subsequent degradation of apoptotic cells is an essential step that occurs throughout life in all multicellular organisms. ELMO/Dock180/Rac proteins are a conserved signalling moduleExpand
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Structural and functional features of central nervous system lymphatics
One of the characteristics of the central nervous system is the lack of a classical lymphatic drainage system. Although it is now accepted that the central nervous system undergoes constant immuneExpand
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A Spatial Gradient of Tau Protein Phosphorylation in Nascent Axons
Mechanisms underlying axonogenesis remain obscure. Although a large number of proteins eventually become polarized to the axonal domain, in no case does protein compartmentalization occur before orExpand
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Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion
Skeletal muscle arises from the fusion of precursor myoblasts into multinucleated myofibres. Although conserved transcription factors and signalling proteins involved in myogenesis have beenExpand
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Activation of mitogen-activated protein kinase associated with prostate cancer progression.
Using an antibody specific for dually phosphorylated extracellular-regulated kinases 1 and 2, we have examined 82 primary and metastatic prostate tumor specimens for the presence of activatedExpand
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Simple: A Sequential Immunoperoxidase Labeling and Erasing Method
The ability to simultaneously visualize expression of multiple antigens in cells and tissues can provide powerful insights into cellular and organismal biology. However, standard methods are limitedExpand
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Synapsins in the vertebrate retina: Absence from ribbon synapses and heterogeneous distribution among conventional synapses
The vertebrate retina contains two ultrastructurally distinct types of vesicle-containing synapses: conventional synapses, made predominantly by amacrine cells, and ribbon synapses, formed byExpand
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Phosphorylation state-specific antibodies: applications in investigative and diagnostic pathology.
  • J. Mandell
  • Biology, Medicine
  • The American journal of pathology
  • 1 November 2003
Until recently, the investigation of protein phosphorylation was limited to biochemical studies of enzyme activities in homogenized tissues. The availability of hundreds of phosphorylationExpand
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Process outgrowth and synaptic varicosity formation by adult photoreceptors in vitro
To assess the regenerative capability of the photoreceptor synapse, we have isolated and cultured photoreceptors from the mature salamander retina. Both rod and cone photoreceptors were able toExpand
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Maximally efficient two-stage screening.
In DNA library screening, blood testing, and monoclonal antibody generation, significant savings in the number of assays can be realized by employing group sampling. Practical considerations oftenExpand
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