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Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study.
BACKGROUND Although tests for occult blood in the feces are widely used to screen for colorectal cancers, there is no conclusive evidence that they reduce mortality from this cause. We evaluated aExpand
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Epidemiology and etiology of Parkinson’s disease: a review of the evidence
The etiology of Parkinson’s disease (PD) is not well understood but likely to involve both genetic and environmental factors. Incidence and prevalence estimates vary to a large extent—at least partlyExpand
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Design of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.
The objectives of the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial are to determine in screenees ages 55-74 at entry whether screening with flexible sigmoidoscopy (60-cmExpand
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Folic acid for the prevention of colorectal adenomas: a randomized clinical trial.
CONTEXT Laboratory and epidemiological data suggest that folic acid may have an antineoplastic effect in the large intestine. OBJECTIVE To assess the safety and efficacy of folic acidExpand
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A randomized trial of aspirin to prevent colorectal adenomas.
BACKGROUND Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel. METHODS We performed a randomized, double-blind trial of aspirin as aExpand
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Calcium supplements for the prevention of colorectal adenomas. Calcium Polyp Prevention Study Group.
BACKGROUND AND METHODS Laboratory, clinical, and epidemiologic evidence suggests that calcium may help prevent colorectal adenomas. We conducted a randomized, double-blind trial of the effect ofExpand
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Glyphosate biomonitoring for farmers and their families: results from the Farm Family Exposure Study.
Glyphosate is the active ingredient in Roundup agricultural herbicides and other herbicide formulations that are widely used for agricultural, forestry, and residential weed control. As part of theExpand
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The non‐Hodgkin lymphomas: A review of the epidemiologic literature
The non‐Hodgkin lymphomas (NHL) are a heterogeneous group of B‐cell and T‐cell neoplasms that arise primarily in the lymph nodes. NHL incidence rates in the US doubled between about 1970 and 1990,Expand
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Colorectal cancer mortality: effectiveness of biennial screening for fecal occult blood.
BACKGROUND In 1993, a randomized controlled trial in Minnesota showed, after 13 years of follow-up, that annual fecal occult blood testing was effective in reducing colorectal cancer mortality by atExpand
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International renal cell cancer study. VII. role of diet
We investigated the role of diet in the etiology of renal cell cancer (RCC) in a multi‐center, population‐based case‐control study conducted in Australia, Denmark, Sweden and the United States, usingExpand
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