• Publications
  • Influence
Experimental chemotherapy with Allium sativum (Liliaceae) methanolic extract in rodents infected with Leishmania major and Leishmania donovani.
TLDR
Since the mechanism of action for the methanolic extract is apparently immunomodulatory, garlic compounds could be purified and tried as complementary medicine in the management of leishmaniases. Expand
Use of the fish endoparasite Ligula intestinalis (L., 1758) in an intermediate cyprinid host (Rastreneobola argentea) for biomonitoring heavy metal contamination in Lake Victoria, Kenya
Use of some fish parasites as bioindicators of heavy metal pollution has been demonstrated as a promising approach because of their capacity to bioconcentrate such elements. This study evaluated theExpand
Contribution of soil, water and food consumption to metal exposure of children from geological enriched environments in the coastal zone of Lake Victoria, Kenya.
TLDR
It is demonstrated that exposure to soil and consumption of higher quantities of some foods contributed to the increased metal body burdens of children in a geologically exposed region. Expand
The Impact of Birth Preparedness on Pregnancy Outcome: Findings from Lurambi Sub County, Kakamega County, Kenya
TLDR
The age of the mother, marital status, ANC attendance, delivery preparations and birth weight were the most significant variables in determining pregnancy outcome and there is need for community education on preparation for birth and its complication. Expand
Combination and monotherapy of Leishmania major infection in BALB/c mice using plant extracts and herbicides.
TLDR
The results of this study demonstrate that combination therapy using alternative administration of saponin, acriflavine, trifluralin and plumbagin is effective in treating L. major infection in mice. Expand
Experimental therapeutic assays of Tephrosia vogelii against Leishmania major infection in murine model: in vitro and in vivo
TLDR
In BALB/c mice where the chemotherapeutic extract was administered intraperitoneally, there was significantly (p < 0.05) larger reduction in lesion size and optimal control of parasite burden than those treated orally, however, standard drugs showed better activity. Expand
Evaluation of leishmanicidal activity and cytotoxicity of Ricinus communis and Azadirachta indica extracts from western Kenya: in vitro and in vivo assays
TLDR
Combination therapy of A. indica and R. communis had best antileishmanial activity than the monotherapies, and an evaluation of the IC50 values of the combination therapies clearly reveals synergistic effects. Expand
Dynamics of metal uptake and depuration in a parasitized cyprinid fish (Rastrineobola argentea).
TLDR
The findings provide evidence that L. intestinalis infection enhances Cd accumulation, but depletes the essential Co in the cyprinid fish R. argentea, concluding that the combined stress of parasites and pollution changes metal risks to fish hosts in a metal specific manner. Expand
Factors Influencing Pregnancy Decision Making among Known HIV Positive Women of Reproductive Age in Busia County, Western Kenya
TLDR
The younger HIV positive women, with 1 or 2 children were three times more likely to get pregnant than older ones despite their HIV positive status and the risks involved to fulfil societal concerns. Expand
In vitro Studies on the Antileishmanial Activity of Herbicides and Plant Extracts Against Leishmania major Parasites
TLDR
The in vitro activity of the test compounds (trifluralin, plumbagin, acriflavine and saponin) against intracellular L. major amastigotes demonstrates the potential of these biocides and herbicides in the treatment of cutaneous leishmaniasis. Expand
...
1
2
...