• Publications
  • Influence
A systematic review of the clinical effectiveness and cost-effectiveness of Pharmalgen® for the treatment of bee and wasp venom allergy.
TLDR
This review assessed the clinical effectiveness and cost-effectiveness of Pharmalgen in providing immunotherapy to individuals with a history of type 1 [immunoglobulin E (IgE)-mediated] systemic allergic reaction to bee and wasp venom and found that PhVIT dominates.
Modelling the cost-effectiveness of human milk and breastfeeding in preterm infants in the United Kingdom
TLDR
It is established that increasing the use of human milk in NICUs in the UK would lead to cost savings to the NHS and more research is needed on the medium and long term health and economic outcomes associated with breastfeeding preterm infants.
The clinical effectiveness and cost-effectiveness of the PROGENSA® prostate cancer antigen 3 assay and the Prostate Health Index in the diagnosis of prostate cancer: a systematic review and economic
TLDR
Evaluating the clinical effectiveness and cost-effectiveness of the PCA3 assay and the phi in the diagnosis of prostate cancer indicated that the use of these tests in the NHS would not be cost-effective.
Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis.
TLDR
A systematic review and meta-analyses of studies on epithelium-off photochemical corneal collagen cross-linkage for the management of keratoconus and secondary ectasia found statistically significant improvements in all efficacy outcomes at 12 months after the operation.
The clinical effectiveness and cost-effectiveness of heated humidified high-flow nasal cannula compared with usual care for preterm infants: systematic review and economic evaluation.
TLDR
There is a lack of convincing evidence suggesting that H HHFNC is superior or inferior to usual care, in particular NCPAP, and uncertainty regarding whether or not HHHFNC can be considered cost-effective.
The costs of functional gastrointestinal disorders and related signs and symptoms in infants: a systematic literature review and cost calculation for England
TLDR
The total cost presented here is likely to be a significant underestimate as only lower bound estimates were used where applicable and for example, costs of alternative therapies, inpatient treatments or diagnostic tests, and time off work by parents could not be adequately estimated and were omitted from the calculation.
Bones of Contention: A Comprehensive Literature Review of Non-SSRI Antidepressant Use and Bone Health
TLDR
It is tentatively suggest that tricyclic antidepressants may increase the risk of fracture via mechanisms other than a direct effect on bone mineral density, and is apparently confined to current users only and is greatest in the earliest stage of treatment, diminishing thereafter.
Misuse and/or treatment delivery failure of inhalers among patients with asthma or COPD: A review and recommendations for the conduct of future research.
TLDR
There is evidence for all identified inhalers that some people may be using them incorrectly, but it is unclear which inhalers have higher rates of misuse or which steps within the inhaler technique are most difficult for patients.
Cenegermin for Treating Neurotrophic Keratitis: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
TLDR
Because of uncertainties with the clinical- and cost-effectiveness evidence, the AC concluded that cenegermin cannot be recommended within its marketing authorisation for NK.
...
1
2
3
4
5
...