J. Magolan

Publications16
h-index6
Citations204
Highly Influential Citations0
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Dimethyl Sulfoxide as a Synthon in Organic Chemistry
Dimethyl sulfoxide is generally characterized as a solvent and oxidant rather than as a substrate, building block, or synthon in organic chemistry. However, an abundance of reports have recently… Expand
  • 54
Total synthesis of (+)-angelmarin.
An efficient 8-step enantioselective total synthesis of (+)-angelmarin, starting from commercially available umbelliferone, has been achieved. Key reactions include olefin cross-metathesis and a Shi… Expand
  • 33
Targeting the resistance of pancreatic cancer cells to nutrient deprivation: anti-austerity compounds.
The emerging "anti-austerity" anti-cancer therapeutic strategy targets the ability of certain cancer cell lines, particularly pancreatic cancer, to survive nutrient deprivation. While biochemical… Expand
  • 15
Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation
Inspired by nature: Angelmarin is an anticancer natural product with potent antiausterity activity, that is, selective cytotoxicity towards nutrient-deprived, resistant cancer cells. Through… Expand
  • 11
Siloxane-terminated phenylpyrimidine liquid crystal hosts
We report the synthesis and characterization of trisiloxane-terminated liquid crystals with 2-phenylpyrimidine cores that form partially bilayered SmA and SmC phases. Variable temperature… Expand
  • 47
Bromination of olefins with HBr and DMSO.
A simple and inexpensive methodology is reported for the conversion of alkenes to 1,2-dibromo alkanes via oxidative bromination using HBr paired with dimethyl sulfoxide, which serves as the oxidant… Expand
  • 37
Cerium-free Luche reduction directed by rehydrated alumina
Abstract A 1,2-regioselective reduction of α,β-unsaturated ketones to their corresponding allylic alcohols is accomplished with NaBH4 in the presence of acidic activated alumina rehydrated to the… Expand
  • 4
Isolation and Synthesis of Veranamine, an Antidepressant Lead from the Marine Sponge Verongula rigida.
The natural product veranamine was isolated from the marine sponge Verongula rigida. It contains a unique heterocyclic scaffold and demonstrates in vivo antidepressant activity and selective affinity… Expand
  • 1
A macrophage-based screen identifies antibacterial compounds selective for intracellular Salmonella Typhimurium
Salmonella Typhimurium (S. Tm) evades the innate immune response by residing within host phagocytes. To identify inhibitors of intracellular S. Tm growth, we performed parallel chemical screens… Expand
  • 1
Efficient Synthesis of Cannabigerol, Grifolin, and Piperogalin via Alumina-Promoted Allylation.
The synthesis of three phenolic natural products has been accomplished with unprecedented efficiency using a new alumina-promoted regioselective aromatic allylation reaction. Cannabigerol and… Expand
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