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A GPU-accelerated and Monte Carlo-based intensity modulated proton therapy optimization system.
PURPOSE Conventional spot scanning intensity modulated proton therapy (IMPT) treatment planning systems (TPSs) optimize proton spot weights based on analytical dose calculations. Expand
Clinically Applicable Monte Carlo-based Biological Dose Optimization for the Treatment of Head and Neck Cancers With Spot-Scanning Proton Therapy.
PURPOSE Our aim is to demonstrate the feasibility of fast Monte Carlo (MC)-based inverse biological planning for the treatment of head and neck tumors in spot-scanning proton therapy. METHODS ANDExpand
A robust intensity modulated proton therapy optimizer based on Monte Carlo dose calculation
An all-scenario robust IMPT optimization based on accurate Monte Carlo (MC) dose calculation was developed to mitigate the effects of uncertainties. Expand
The Data Acquisition System for the KOTO Detector
The KOTO experiment is located at Japan Proton Accelerator Research Complex at Tokai, Japan. Expand
Monte-Carlo-based 4D robust optimization using physical and temporal uncertainties for intensity-modulated proton therapy
Purpose: Respiratory motion and the interplay effect cause the dose delivered to a patient with spot-scanned proton therapy to differ from the dose planned for during optimization. A new 4D robustExpand
Robust radiobiological optimization of ion beam therapy utilizing Monte Carlo and microdosimetric kinetic model.
PURPOSE To develop a Monte Carlo (MC)-based and robust ion beam therapy optimization system that separates the optimization algorithm from the relative biological effectiveness (RBE) modeling.Expand