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Clinical, neuroradiological and genetic findings in pontocerebellar hypoplasia.
Pontocerebellar hypoplasia is a group of autosomal recessive neurodegenerative disorders with prenatal onset. The common characteristics are cerebellar hypoplasia with variable atrophy of the… Expand
Functional plasticity of language-related brain areas after cochlear implantation.
Using PET, the cerebral network engaged by heard language processing in normal hearing subjects was compared with that in patients who received a cochlear implant after a period of profound deafness.… Expand
Diffusion tensor imaging for the assessment of upper motor neuron integrity in ALS
Background: High angular resolution diffusion tensor imaging (HARD) is an MRI technique that exploits the mobility of water molecules to yield maps of structural order and directionality of white… Expand
Hallucinosis in idiopathic Parkinson’s disease
- J. M. Graham, R. Grünewald, H. Sagar
- Psychology, Medicine
- Journal of neurology, neurosurgery, and…
- 1 October 1997
BACKGROUND Hallucinosis is a complication of the treatment of idiopathic Parkinson’s disease commonly thought to afflict older, chronically medicated, cognitively impaired patients. However, patients… Expand
Cross-Modal Plasticity Underpins Language Recovery after Cochlear Implantation
Postlingually deaf subjects learn the meaning of sounds after cochlear implantation by forming new associations between sounds and their sources. Implants generate coarse frequency responses,… Expand
A data‐driven approach to the study of heterogeneity in idiopathic Parkinson's disease: identification of three distinct subtypes
- J. M. Graham, H. Sagar
- Psychology, Medicine
- Movement disorders : official journal of the…
- 1 January 1999
Idiopathic Parkinson's disease (IPD) has been subclassified on the basis of predominant motor symptomatology, age at disease onset, depressive affect, and cognitive performance. However, subgroups… Expand
Dual-purpose canola—a new opportunity in mixed farming systems
The term dual-purpose canola describes the use of a canola crop for forage before seed production. It could potentially provide a profitable and flexible break-crop option for mixed farms, but there… Expand
Brain iron deposition in Parkinson's disease imaged using the PRIME magnetic resonance sequence.
- J. M. Graham, M. Paley, R. Grünewald, N. Hoggard, P. Griffiths
- Brain : a journal of neurology
- 1 December 2000
Iron content of the basal ganglia was investigated in 25 patients with idiopathic Parkinson's disease and 14 matched healthy control subjects using a partially refocused interleaved multiple echo… Expand
Association study of dopamine receptor gene polymorphisms with drug-induced hallucinations in patients with idiopathic Parkinson's disease.
Some patients with idiopathic Parkinson's disease experience hallucinations as a result of treatment with levodopa and dopamine agonists. There is evidence for some heterogeneity in these… Expand
Rapid separation of LDL subclasses by iodixanol gradient ultracentrifugation.
BACKGROUND A predominance of small, dense LDL (sdLDL) confers in excess of a threefold increase in coronary heart disease (CHD) risk. The conventional method for the detection of sdLDL, salt density… Expand