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Oxidants and antioxidants in disease: oxidative stress in farm animals.
Important infectious diseases in farm animals, such as pneumonia and enteritis, are thought to be associated with the so-called oxidative stress, i.e. a chemical phenomenon involving an imbalance inExpand
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Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking.
  • J. Lykkesfeldt
  • Chemistry, Medicine
  • Clinica chimica acta; international journal of…
  • 1 May 2007
Thiobarbituric acid reactive substances (TBARS) and malondialdehyde (MDA) have been used as biomarkers of lipid oxidation for more than thirty years. The validity of these biomarkers has beenExpand
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Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials
In contrast to the promised ‘antioxidant miracle’ of the 1980s, several randomised controlled trials have shown no effect of antioxidant supplements on hard endpoints such as morbidity and mortality.Expand
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Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with
Determination of dehydroascorbic acid in biological samples most commonly involves indirect measurement. The concentration is calculated by subtraction of the measured ascorbic acid concentrationExpand
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Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
Non-alcoholic fatty liver disease (NAFLD) is currently the world’s most common liver disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic steatosis, NAFLD isExpand
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Antioxidant supplementation does not alter endurance training adaptation.
BACKGROUND There is a considerable commercial market, especially within the sports community, claiming the need for antioxidant supplementation. One argument for antioxidant supplementation in sportsExpand
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Feeding acetyl-l-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
  • T. Hagen, J. Liu, +5 authors B. Ames
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences…
  • 19 February 2002
Mitochondrial-supported bioenergetics decline and oxidative stress increases during aging. To address whether the dietary addition of acetyl-l-carnitine [ALCAR, 1.5% (wt/vol) in the drinking water]Expand
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Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity.
Mitochondrial function and ambulatory activity were monitored after feeding old rats acetyl-L-carnitine (ALCAR). Young (3-5 mo) and old (22-28 mo) rats were given a 1.5% (wt/vol) solution of ALCAR inExpand
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Determination of ascorbic acid and dehydroascorbic acid in plasma by high-performance liquid chromatography with coulometric detection--are they reliable biomarkers of oxidative stress?
The concentrations of the hydrophilic antioxidants ascorbic acid and dehydroascorbic acid in plasma for some time have been considered possible biomarkers of oxidative stress. However, severalExpand
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The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs.
The effect of route of administration and dose of enrofloxacin (Baytril) on the development of fluoroquinolone resistance in Salmonella and Escherichia coli in the intestinal tract of pigs wasExpand
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