Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Oxidants and antioxidants in disease: oxidative stress in farm animals.
- J. Lykkesfeldt, O. Svendsen
- Medicine
- Veterinary journal
- 1 May 2007
Important infectious diseases in farm animals, such as pneumonia and enteritis, are thought to be associated with the so-called oxidative stress, i.e. a chemical phenomenon involving an imbalance in… Expand
Malondialdehyde as biomarker of oxidative damage to lipids caused by smoking.
- J. Lykkesfeldt
- Chemistry, Medicine
- Clinica chimica acta; international journal of…
- 1 May 2007
Thiobarbituric acid reactive substances (TBARS) and malondialdehyde (MDA) have been used as biomarkers of lipid oxidation for more than thirty years. The validity of these biomarkers has been… Expand
Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials
- J. Lykkesfeldt, H. Poulsen
- Medicine
- British Journal of Nutrition
- 15 December 2009
In contrast to the promised ‘antioxidant miracle’ of the 1980s, several randomised controlled trials have shown no effect of antioxidant supplements on hard endpoints such as morbidity and mortality.… Expand
Determination of ascorbic acid and dehydroascorbic acid in biological samples by high-performance liquid chromatography using subtraction methods: reliable reduction with…
- J. Lykkesfeldt
- Medicine, Chemistry
- Analytical biochemistry
- 15 June 2000
Determination of dehydroascorbic acid in biological samples most commonly involves indirect measurement. The concentration is calculated by subtraction of the measured ascorbic acid concentration… Expand
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
- D. H. Ipsen, J. Lykkesfeldt, P. Tveden-Nyborg
- Medicine
- Cellular and Molecular Life Sciences
- 23 June 2018
Non-alcoholic fatty liver disease (NAFLD) is currently the world’s most common liver disease, estimated to affect up to one-fourth of the population. Hallmarked by hepatic steatosis, NAFLD is… Expand
Antioxidant supplementation does not alter endurance training adaptation.
- C. Yfanti, T. Åkerström, +7 authors B. Pedersen
- Medicine
- Medicine and science in sports and exercise
- 1 July 2010
BACKGROUND
There is a considerable commercial market, especially within the sports community, claiming the need for antioxidant supplementation. One argument for antioxidant supplementation in sports… Expand
Feeding acetyl-l-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
- T. Hagen, J. Liu, +5 authors B. Ames
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences…
- 19 February 2002
Mitochondrial-supported bioenergetics decline and oxidative stress increases during aging. To address whether the dietary addition of acetyl-l-carnitine [ALCAR, 1.5% (wt/vol) in the drinking water]… Expand
Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity.
- T. Hagen, R. T. Ingersoll, +5 authors B. Ames
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 4 August 1998
Mitochondrial function and ambulatory activity were monitored after feeding old rats acetyl-L-carnitine (ALCAR). Young (3-5 mo) and old (22-28 mo) rats were given a 1.5% (wt/vol) solution of ALCAR in… Expand
Determination of ascorbic acid and dehydroascorbic acid in plasma by high-performance liquid chromatography with coulometric detection--are they reliable biomarkers of oxidative stress?
- J. Lykkesfeldt, S. Loft, H. Poulsen
- Chemistry, Medicine
- Analytical biochemistry
- 1 August 1995
The concentrations of the hydrophilic antioxidants ascorbic acid and dehydroascorbic acid in plasma for some time have been considered possible biomarkers of oxidative stress. However, several… Expand
The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs.
- C. Wiuff, J. Lykkesfeldt, O. Svendsen, F. Aarestrup
- Biology, Medicine
- Research in veterinary science
- 1 December 2003
The effect of route of administration and dose of enrofloxacin (Baytril) on the development of fluoroquinolone resistance in Salmonella and Escherichia coli in the intestinal tract of pigs was… Expand