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The International Neuroblastoma Pathology Classification (the Shimada system)
The International Neuroblastoma Pathology Committee, which is comprised of six member pathologists, was convened with the objective of proposing a prognostically significant and biologically relevantExpand
Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease
The identification of mutations in CXCR4 in individuals with WHIM syndrome represents the first example of aberrant chemokine receptor function causing human disease and suggests that the receptor may be important in cell-mediated immunity to HPV infection. Expand
International neuroblastoma pathology classification for prognostic evaluation of patients with peripheral neuroblastic tumors
The International Neuroblastoma Pathology Classification was established in 1999 for the prognostic evaluation of patients with neuroblastic tumors (NTs).
Revision of the International Neuroblastoma Pathology Classification
Ganglioneuroblastoma, nodular can be divided into two prognostic subsets, a favorable subset (FS) and an unfavorable subset (US) of an unfavorable histology group. Expand
Reduction in central nervous system leukemia with a pharmacokinetically derived intrathecal methotrexate dosage regimen.
During the period 1976-1981, 3241 children were enrolled on three major studies of acute lymphoblastic leukemia by participating institutions of the Children's Cancer Study Group. Each study includedExpand
Biologic variables in the outcome of stages I and II neuroblastoma treated with surgery as primary therapy: a children's cancer group study.
Children with stages I and II neuroblastoma have 98% survival with surgery alone as primary therapy and a subset of patients at higher risk for death can be defined as those with stage II disease who have tumor MYCN amplification or who are >/= 2 years of age with either unfavorable histopathology or positive lymph nodes. Expand
Augmented post-induction therapy for children with high-risk acute lymphoblastic leukemia and a slow response to initial therapy.
Augmented post-induction chemotherapy results in an excellent outcome for most patients with high-risk ALL and a slow response to initial therapy. Expand
Analysis of prognostic factors in acute lymphoblastic leukemia.
Children with ALL who have a high probability of excellent response, long-term survival, and cure when treated with widely available standard therapy when treatment with widely Available standard therapy can be identified at the time of diagnosis. Expand
Successful treatment of stage III neuroblastoma based on prospective biologic staging: a Children's Cancer Group study.
The excellent survival of the biologically favorable group and the historically improved EFS of the biological unfavorable group suggest that biologic staging should be used to define the prognosis and treatment of stage III neuroblastoma. Expand
Comparisons of telomere lengths in peripheral blood and cerebellum in Alzheimer's disease
This work examined the correlation between PBL and cerebellum telomere length in AD patients, and compared telomeres lengths in cerebella from individuals with AD versus age‐matched control subjects. Expand