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HYPOCRELLINS and THEIR USE IN PHOTOSENSITIZATION *
TLDR
The review summarizes the chemical and photophysical properties of the hypocrellins and their derivatives as well as studies on photosensitization to date at the molecular, cellular and in vivo levels, and their prospects as PDT agents.
Synthetic DNA minor groove-binding drugs.
DNA sequence selectivities in the covalent bonding of antibiotic saframycins Mx1, Mx3, A, and S deduced from MPE.Fe(II) footprinting and exonuclease III stop assays.
DNA sequence selectivities in the covalent binding of the antitumor antibiotic saframycins Mx1, Mx3, A, and S have been determined by complementary strand MPE.Fe(II) footprinting and exonuclease III
Podophyllotoxins: current status and recent developments.
TLDR
This article review, the progress of podophyllotoxins from its early applications in folk medicine to the most recent modifications and the mechanism(s) of action, pharmacology and the structure-activity relationships.
Photosensitization of human leukemic cells by anthracenedione antitumor agents.
TLDR
No evidence of photo-induced membrane damage, as determined by transport of the model amino acid cycloleucine, could be observed even at supralethal doses, and neither ametantrone nor mitoxantrone gave a decreased viability upon illumination.
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