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Synthesis and some pharmacological properties of [4-threonine, 7-glycine]oxytocin, [1-(L-2-hydroxy-3-mercaptopropanoic acid), 4-threonine, 7-glycine]oxytocin (hydroxy[Thr4, Gly7]oxytocin), and…
- J. Lowbridge, M. Manning, J. Haldar, W. H. Sawyer
- Biology, ChemistryJournal of medicinal chemistry
- 1977
TLDR
The design of effective in vivo antagonists of rat uterus and milk ejection responses to oxytocin.
- W. Sawyer, J. Haldar, M. Manning
- BiologyEndocrinology
- 1980
TLDR
[1-deaminopenicillamine,4-valine]-8-D-arginine-vasopressin, a highly potent inhibitor of the vasopressor response to arginine-vasopressin.
- M. Manning, J. Lowbridge, C. Stier, J. Haldar, W. Sawyer
- Biology, MedicineJournal of medicinal chemistry
- 1 September 1977
TLDR
[1-(beta-mercapto-beta,beta-cyclopentamethylenepropionic acid),4-valine,-8-D-arginine]vasopressin, a potent and selective inhibitor of the vasopressor response to arginine-vasopressin.
- J. Lowbridge, M. Manning, J. Haldar, W. Sawyer
- Biology, MedicineJournal of medicinal chemistry
- 1 March 1978
TLDR
[1-Deaminopenicillamine,4-threonine]oxytocin, a potent inhibitor of oxytocin.
- M. Manning, J. Lowbridge, J. Seto, J. Haldar, W. Sawyer
- Biology, ChemistryJournal of medicinal chemistry
- 1 February 1978
TLDR
Synthetic antagonists of in vivo responses by the rat uterus to oxytocin.
- J. Lowbridge, M. Manning, J. Seto, J. Haldar, W. Sawyer
- Biology, ChemistryJournal of medicinal chemistry
- 1 May 1979
TLDR
Design of neurohypophyseal peptides that exhibit selective agonistic and antagonistic properties.
- M. Manning, J. Lowbridge, J. Haldar, W. H. Sawyer
- Biology, MedicineFederation proceedings
- 1 May 1977
TLDR
[1-(L-2-hydroxy-3-mercaptopropanoic acid)] analogues of arginine-vasopressin, [8-D-arginine]vasopressin, and [4-valine,8-D-arginine]vasopressin.
- J. Lowbridge, M. Manning, J. Haldar, W. Sawyer
- Biology, ChemistryJournal of medicinal chemistry
- 1 September 1977
TLDR
Studies on the extended active site of papain.
- J. Lowbridge, J. Fruton
- Chemistry, BiologyThe Journal of biological chemistry
- 10 November 1974
The molecular conformation of cyclotri-β-alanyl
- D. White, Christopher Morrow, P. J. Cox, C. Drey, J. Lowbridge
- Chemistry
- 1975
The title compound has been studied by molecular mechanics calculations. There is no single, well defined global minimum energy conformation and the low energy conformations are unrelated to the…
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