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Effects of static muscular contraction on impulse activity of groups III and IV afferents in cats.
TLDR
The results suggest that although both groups III and IV muscle afferents contribute to the reflex cardiovascular increases evoked by static exercise, group III fibers were likely to be stimulated by the mechanical effects of muscular contraction, whereas at least some group IV fibers werelikely to be stimulating by the metabolic products of muscular contractions.
Air Pollution Exposures and Circulating Biomarkers of Effect in a Susceptible Population: Clues to Potential Causal Component mixtures and mechanisms
TLDR
Traffic-related air pollutants are associated with increased systemic inflammation, increased platelet activation, and decreased erythrocyte antioxidant enzyme activity, which may be partly behind air pollutant–related increases in systemic inflammation.
Circulating Biomarkers of Inflammation, Antioxidant Activity, and Platelet Activation Are Associated with Primary Combustion Aerosols in Subjects with Coronary Artery Disease
TLDR
It is suggested that traffic emission sources of OCpri and quasi-ultrafine particles lead to increased systemic inflammation and platelet activation and decreased antioxidant enzyme activity in elderly people with CAD.
Traffic-related Air Pollution and Blood Pressure in Elderly Subjects With Coronary Artery Disease
TLDR
Exposure to primary organic components of fossil fuel combustion near the home were strongly associated with increased ambulatory BP in a population at potential risk of heart attack, suggesting low fitness or obesity may increase the effects of pollutants.
Limitation of reperfusion injury by a monoclonal antibody to C5a during myocardial infarction in pigs.
TLDR
Myocardial infarction-reperfusion is associated with activation of the alternative complement pathway and C5a in the propagation of ischemia cardiac damage during reperfusion, and a MAb to C4a that inhibits neutrophil cytotoxic activity, but neither the membrane attack complex nor myocardial neutrophils accumulation, decreases infarct size in pigs.
Reflex effect of skeletal muscle mechanoreceptor stimulation on the cardiovascular system.
TLDR
When the triceps surae were stretched passively to produce a pattern and amount of tension similar to that seen during static hindlimb contraction, a significant reflex cardiovascular response occurred.
Production of hydroxyl radicals in contracting skeletal muscle of cats.
TLDR
Results directly demonstrate that .OH is produced in vivo in the skeletal muscle of cats during intermittent static contraction and that production can occur before the onset of fatigue.
Sensitization of group III muscle afferents to static contraction by arachidonic acid.
TLDR
It is concluded that both cyclooxygenase and lipoxygen enzyme products of arachidonic acid metabolism sensitize group III muscle afferents to static contraction.
Effects of Capsaicin and Bradykinin on Afferent Fibers with Endings in Skeletal Muscle
TLDR
The results suggest that group IV muscle afferents are primarily responsible for causing the reflex increases in cardiovascular function evoked by injecting capsaicin into the arterial supply of the skinned hindlimb of dogs.
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