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A Subpopulation of Olfactory Bulb GABAergic Interneurons Is Derived from Emx1- and Dlx5/6-Expressing Progenitors
The subventricular zone (SVZ) of the postnatal brain continuously generates olfactory bulb (OB) interneurons. We show that calretinin+, calbindin+, and dopaminergic (TH+) periglomerular OBExpand
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Short- and Long-Range Attraction of Cortical GABAergic Interneurons by Neuregulin-1
Most cortical interneurons arise from the subcortical telencephalon, but the molecules that control their migration remain largely unidentified. Here, we show that different isoforms of Neuregulin-1Expand
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CXCR4 and CXCR7 Have Distinct Functions in Regulating Interneuron Migration
CXCL12/CXCR4 signaling is critical for cortical interneuron migration and their final laminar distribution. No information is yet available on CXCR7, a newly defined CXCL12 receptor. Here weExpand
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Distinct molecular pathways for development of telencephalic interneuron subtypes revealed through analysis of Lhx6 mutants
Here we analyze the role of the Lhx6 lim‐homeobox transcription factor in regulating the development of subsets of neocortical, hippocampal, and striatal interneurons. An Lhx6 loss‐of‐functionExpand
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FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development
BackgroundGrowth, differentiation and regional specification of telencephalic domains, such as the cerebral cortex, are regulated by the interplay of secreted proteins produced by patterning centersExpand
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DLX5 Regulates Development of Peripheral and Central Components of the Olfactory System
Induction, neurogenesis, and synaptogenesis of the olfactory bulb are thought to require interactions with the olfactory epithelium. TheDlx family of homeobox genes is expressed in both the olfactoryExpand
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Cellular patterns of transcription factor expression in developing cortical interneurons.
Most gamma-aminobutyric acidergic interneurons in the neocortex and hippocampus are derived from subpallial progenitors in the medial ganglionic eminence and migrate tangentially to the pallium,Expand
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Lhx6 and Lhx8 Coordinately Induce Neuronal Expression of Shh that Controls the Generation of Interneuron Progenitors
Lhx6 and Lhx8 transcription factor coexpression in early-born MGE neurons is required to induce neuronal Shh expression. We provide evidence that these transcription factors regulate expression of aExpand
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Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain
Prevailing notions of cerebral vascularization imply that blood vessels sprout passively into the brain parenchyma from pial vascular plexuses to meet metabolic needs of growing neuronal populations.Expand
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Dlx-Dependent and -Independent Regulation of Olfactory Bulb Interneuron Differentiation
Olfactory bulb interneuron development is a complex multistep process that involves cell specification in the ventral telencephalon, tangential migration into the olfactory bulb, and local neuronalExpand
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