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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the… Expand
Effects of crocin on reperfusion-induced oxidative/nitrative injury to cerebral microvessels after global cerebral ischemia
This paper studied the effects of crocin, a pharmacologically active component of Crocus sativus L., on ischemia/reperfusion (I/R) injury in mice cerebral microvessels. Transient global cerebral… Expand
The effect of Sailuotong (SLT) on neurocognitive and cardiovascular function in healthy adults: a randomised, double-blind, placebo controlled crossover pilot trial
- G. Steiner, A. Yeung, +6 authors Dennis H Chang
- BMC Complementary and Alternative Medicine
- 1 December 2015
BackgroundSailuotong (SLT) is a standardised herbal medicine formula consisting of Panax ginseng, Ginkgo biloba, and Crocus sativus, and has been designed to enhance cognitive and cardiovascular… Expand
Ginsenoside Rd promotes neurogenesis in rat brain after transient focal cerebral ischemia via activation of PI3K/Akt pathway
Aim:To investigate the effects of ginsenoside Rd (Rd) on neurogenesis in rat brain after ischemia/reperfusion injury (IRI).Methods:Male SD rats were subjected to transient middle cerebral artery… Expand
Repeated administration of Sailuotong, a fixed combination of Panax ginseng, Ginkgo biloba, and Crocus sativus extracts for vascular dementia, alters CYP450 activities in rats.
- Y. Zhang, Lan Miao, L. Lin, C. Ren, J. Liu, Yi-min Cui
- Phytomedicine : international journal of…
BACKGROUND Sailuotong (SLT) is a standard Chinese preparation made from extracts of Panax ginseng (ginseng), Ginkgo biloba (ginkgo), and Crocus sativus (saffron). Preliminary clinical trials and… Expand
Salvianolic acid A promotes the acceleration of neovascularization in the ischemic rat myocardium and the functions of endothelial progenitor cells.
ETHNOPHARMACOLOGICAL RELEVANCE Salvia miltiorrhiza (SM, also known as DanShen) is one of the well-known widely used Chinese herbal medicines in clinical, containing phenolic compounds and potent… Expand
Protective Effect of Kaempferol on LPS plus ATP-Induced Inflammatory Response in Cardiac Fibroblasts
Inflammatory response is an important mechanism in the pathogenesis of cardiovascular diseases. Cardiac fibroblasts play a crucial role in cardiac inflammation and might become a potential… Expand
Pro-angiogenic actions of Salvianolic acids on in vitro cultured endothelial progenitor cells and chick embryo chorioallantoic membrane model.
- Y. Li, Chang-ling Duan, J. Liu, Yong-gang Xu
- Medicine, Biology
- Journal of ethnopharmacology
- 5 October 2010
AIM OF THE STUDY Salvia miltiorrhiza (SM, also known as DanShen) is one of the well-known widely-used Chinese herbal medicines in clinical practice. In this study we aimed to demonstrate the… Expand
RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats
AbstractAim:To test the role of the Beclin 1-dependent autophagy pathway in brain damage during cerebral ischemia.Methods:Focal cerebral ischemia was established in rats using a middle cerebral… Expand
Gene expression profile induced by oral administration of baicalin and gardenin after focal brain ischemia in rats
- Zhan-jun Zhang, Z. Wang, X. Zhang, K. Ying, J. Liu, Y. Wang
- Acta Pharmacologica Sinica
- 1 March 2005
AbstractAim:To investigate differential gene expression and the pharmacological mechanism of baicalin and gardenin in focal cerebral ischemia in rats with high-density cDNA microarray.Methods:Rat… Expand