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Removal of xenoreactive human anti-pig antibodies by absorption on recombinant mucin-containing glycoproteins carrying the Gal alpha1,3Gal epitope.
BACKGROUND The hyperacute rejection caused by preformed natural antibodies in the recipient species reacting with donor species endothelial antigens is one of the major obstacles preventing routineExpand
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Anti-pig antibody adsorption efficacy of {alpha}-Gal carrying recombinant P-selectin glycoprotein ligand-1/immunoglobulin chimeras increases with core 2 {beta}1, 6-N-acetylglucosaminyltransferase
We have previously described the construction of a P-selectin glycoprotein ligand-1-mouse immunoglobulin Fc fusion protein, which when transiently coexpressed with the porcine alpha1,3Expand
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Multivalent Galα1,3Gal‐substitution makes recombinant mucin–immunoglobulins efficient absorbers of anti‐pig antibodies
Liu J, Weintraub A, Holgersson J. Multivalent Galα1,3Gal‐substitution makes recombinant mucin–immunoglobulins efficient absorbers of anti‐pig antibodies. Xenotransplantation 2003; 10: 149–163. ©Expand
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T cell receptor V alpha gene usage in human T cells stimulated with SEE and SED.
V alpha gene usage in human T cells stimulated with SEE and SED was investigated by using polymerase chain reaction with specific primers. V beta 8 T cells from normal blood donors PBMC were sortedExpand
Proteines hybrides et procedes de fabrication
L'invention concerne des compositions et des procedes de traitement ou de prevention de rejet suraigu.