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A Deep Learning-Based Radiomics Model for Prediction of Survival in Glioblastoma Multiforme
It is demonstrated that transfer learning-based deep features are able to generate prognostic imaging signature for OS prediction and patient stratification for GBM, indicating the potential of deep imaging feature-based biomarker in preoperative care of GBM patients. Expand
Reducing Plasma Membrane Sphingomyelin Increases Insulin Sensitivity
It is concluded that Sptlc2 heterozygous deficiency- or Sms2 deficiency-mediated reduction of SM in the plasma membranes leads to an improvement in tissue and whole-body insulin sensitivity. Expand
An enzyme linked immunosorbent assay for the determination of cyromazine and melamine residues in animal muscle tissues
Abstract Cyromazine and its metabolite melamine are toxic to animal and human. Herein this paper, an indirect competitive enzyme linked immunosorbent assay (ELISA) was first developed for theExpand
Characterization of frequently mutated cancer genes in Chinese breast tumors: a comparison of Chinese and TCGA cohorts.
The mutational landscape of cancer genes in Chinese breast cancer was elucidated and significant genomic differences between Asian and Caucasian patients were identified, including a significantly higher prevalence for TP53 and AKT1 in Chinese patients. Expand
Comprehensive analysis of correlations among codon usage bias, gene expression, and substitution rate in Arachis duranensis and Arachis ipaënsis orthologs
Gene expression differed between single-copy and multiple-copy genes as well as sequences with signatures of positive and purifying selection, and was significantly higher for single- copy genes than for multiple- Copy genes. Expand
Chitosan promoting formononetin and calycosin accumulation in Astragalus membranaceus hairy root cultures via mitogen-activated protein kinase signaling cascades
The findings in this work not only highlight a feasible chitosan elicitation practice to enhance the in vitro production of two bioactive isoflavones for nutraceutical and food applications, but also contribute to understanding the phytoalexin biosynthesis in response to chitotoxic elicitation. Expand
Proteomic Analysis of the Rat Ovary Following Chronic Low-Dose Exposure to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)
Data provide further insight into the mechanisms by which TCDD disrupts ovarian function by indicating which differential protein expressions following low-dose T CDD exposure are upregulated and downregulated. Expand
Increased glycophorin A somatic cell variant frequency in arsenic-exposed patients of Guizhou, China.
It is demonstrated that arsenic exposure is associated with mutations at the GPA locus, an effect exaggerated in patients bearing arsenic-induced skin tumors, and the variant frequency of GPA could be a useful biomarker for arsenic exposure and arsenic carcinogenesis. Expand
Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium
Recent novel findings that elucidate how respiratory viral infections alter the epithelial barrier in the airways, the upper airway microbial environment, epigenetic modifications including miRNA modulation, and other changes in immune responses throughout the upper and lower airways are focused on. Expand
Implications of C1q/TNF-related protein superfamily in patients with coronary artery disease
Findings suggest CTRPs may be the superior predictive factors for the vascular lesion of CAD and represent novel therapeutic targets against CAD. Expand