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Dlx genes encode DNA‐binding proteins that are expressed in an overlapping and sequential pattern during basal ganglia differentiation
TLDR
It is found that the Dlx genes are expressed in overlapping patterns at different stages of differentiation within the primordia of the basal ganglia, suggesting that each of these DlX genes may have a distinct role in different steps of differentiation in the basal Ganglia. Expand
Engineering CAR-T cells
TLDR
The structure and evolution of chimeric antigen receptors are discussed, and the tools used for production of CAR-T cells are reported on, to address the challenges posed by the technology. Expand
Genetic mutations in nonsyndromic deafness patients of Chinese minority and han ethnicities in Yunnan, China
TLDR
The molecular etiology of nonsyndromic deafness in the Yunnan Province population where more than 52 minorities live has not been thoroughly investigated and 35.74% deaf patients showed evidence of genetic involvement, based on either genetic screening or family history. Expand
Early responses of osteoblast-like cells to different mechanical signals through various signaling pathways.
TLDR
Early cellular responses were connected with cytoskeleton and RTK pathways during the transduction of mechanical signals, and the property of strains was an influential factor for the activation effects. Expand
MicroRNAs Associated With HBV Infection And HBV-related HCC
TLDR
The roles of mi RNAs in HBV infection, the recently identified mechanism underlying dysregulation of miRNAs inHBV-associated HCC, and their association with hepatocarcinogenesis are summarized. Expand
Nonintubated Video-Assisted Thoracoscopic Surgery Under Epidural Anesthesia Compared With Conventional Anesthetic Option
TLDR
VATS under anesthesia with nontracheal intubation is safe and feasible, and has demonstrated advantages, including shorter postoperative fasting time, shorter duration of antibiotic use, and shorter hospital stay, compared with VATS under general anesthesia with double lumen tube. Expand
A comparative study of transulnar and transradial artery access for percutaneous coronary intervention in patients with acute coronary syndrome.
TLDR
The TUI approach has results and access complications similar to the TRI approach and is a safe and feasible alternative for ACS patients. Expand
Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling.
TLDR
It is demonstrated that elevated expression of RAGE, ER stress marker glucose-regulated protein 78 (GRP78), and cell-cycle regulator p21 was all positively correlated with enhanced senescence-associated- β-galactosidase (SA-β-gal) activity in DN patients. Expand
Microbial communities evolve faster in extreme environments
TLDR
The rERs of microbial communities are mainly shaped by environmental conditions, and the microbes inhabiting extreme habitats (acid mine drainage, saline lake and hot spring) evolve faster than those populating benign environments (surface ocean, fresh water and soil). Expand
Metformin inhibits renal cell carcinoma in vitro and in vivo xenograft.
TLDR
The results suggest that metformin may be a potential therapeutic agent for the treatment of RCC and induce G0/G1 cell cycle arrest and inhibit RCC growth in vitro and in vivo. Expand
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