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Molecular Cloning and Disease Association of Hepatitis G Virus: A Transfusion-Transmissible Agent
An RNA virus, designated hepatitis G virus (HGV), was identified from the plasma of a patient with chronic hepatitis. Extension from an immunoreactive complementary DNA clone yielded the entire… Expand
Virus and antibody dynamics in acute west nile virus infection.
- M. Busch, S. Kleinman, +9 authors S. Caglioti
- The Journal of infectious diseases
- 1 October 2008
BACKGROUND The dynamics of the early stages of West Nile virus (WNV) infection can be assessed by follow-up studies of viremic blood donors. METHODS A total of 245 donors with WNV viremia were… Expand
Screening the blood supply for West Nile virus RNA by nucleic acid amplification testing.
- M. Busch, S. Caglioti, +7 authors S. Kleinman
- Biology, Medicine
- The New England journal of medicine
- 4 August 2005
BACKGROUND The use of nucleic acid amplification tests of "minipools" of 16 samples to screen blood donors for West Nile virus RNA began in July 2003. We report the yield and characteristics of… Expand
Dengue viremia in blood donors identified by RNA and detection of dengue transfusion transmission during the 2007 dengue outbreak in Puerto Rico
BACKGROUND: In 2007, a total of 10,508 suspected dengue cases were reported in Puerto Rico. Blood donations were tested for dengue virus (DENV) RNA and recipients of RNA‐positive donations traced to… Expand
Dengue viremia in blood donors from Honduras, Brazil, and Australia
BACKGROUND: Dengue fever and hemorrhagic disease are caused by four dengue virus (DENV) serotypes (DENV‐1 to ‐4), mosquito‐borne flaviviruses with increasing incidence, and expanding global… Expand
Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis
We report unbiased metagenomic detection of chikungunya virus (CHIKV), Ebola virus (EBOV), and hepatitis C virus (HCV) from four human blood samples by MinION nanopore sequencing coupled to a newly… Expand
Evidence for Persistent Low-Level Viremia in Individuals Who Control Human Immunodeficiency Virus in the Absence of Antiretroviral Therapy
ABSTRACT A subset of antiretroviral-untreated, human immunodeficiency virus (HIV)-infected individuals are able to maintain undetectable plasma HIV RNA levels in the absence of antiretroviral… Expand
Dengue virus in blood donations, Puerto Rico, 2005
BACKGROUND: A single instance of transfusion‐transmitted dengue infection has been reported. The high incidence of dengue in endemic countries, the high proportion of asymptomatic infection, and the… Expand
Highly Sensitive Detection of Dengue Virus Nucleic Acid in Samples from Clinically Ill Patients
- J. Muñoz-Jordán, C. Collins, +4 authors J. Linnen
- Medicine, Biology
- Journal of Clinical Microbiology
- 18 February 2009
ABSTRACT Dengue virus (DENV) is a major cause of febrile illness and hemorrhagic fever in tropical and subtropical regions. Typically, patients presenting with acute dengue disease are viremic but… Expand
Seroprevalence of hepatitis E virus (HEV) and detection of HEV RNA with a transcription‐mediated amplification assay in blood donors from Catalonia (Spain)
Hepatitis E virus (HEV) is an emerging threat to the safety of blood transfusion. The aim of this study was to determine HEV immunoglobulin (Ig)G and RNA prevalence in Catalan blood donors.