J. Liepins

Publications37
h-index7
Citations168
Highly Influential Citations3
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Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.
AIMS Trimethylamine-N-oxide (TMAO) is produced in host liver from trimethylamine (TMA). TMAO and TMA share common dietary quaternary amine precursors, carnitine and choline, which are metabolized by… Expand
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Mildronate, the inhibitor of L-carnitine transport, induces brain mitochondrial uncoupling and protects against anoxia-reoxygenation.
The preservation of mitochondrial function is essential for normal brain function after ischaemia-reperfusion injury. l-carnitine is a cofactor involved in the regulation of cellular energy… Expand
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Drying enhances immunoactivity of spent brewer's yeast cell wall β-D-glucans.
Due to immunological activity, microbial cell wall polysaccharides are defined as 'biological response modifiers' (BRM). Cell walls of spent brewer's yeast also have some BRM activity. However, up to… Expand
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Model-based biotechnological potential analysis of Kluyveromyces marxianus central metabolism
The non-conventional yeast Kluyveromyces marxianus is an emerging industrial producer for many biotechnological processes. Here, we show the application of a biomass-linked stoichiometric model of… Expand
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Adenine auxotrophy--be aware: some effects of adenine auxotrophy in Saccharomyces cerevisiae strain W303-1A.
Adenine auxotrophy is a commonly used genetic marker in haploid yeast strains. Strain W303-1A, which carries the ade2-1 mutation, is widely used in physiological and genetic research. Yeast… Expand
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Effects of acetate on Kluyveromyces marxianus DSM 5422 growth and metabolism
Metabolically active cells produce a wide array of metabolites that can inhibit their growth. Acetate is a widely known preservative, and it is also produced by yeast cells during their growth.… Expand
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The impact of calcium ions on commercially available β-galactosidase
Commercial lactose hydrolysing enzymes producers provide purchasers with information as optimal enzyme temperature and pH, as well recommended amount of enzyme. However, there are also other indices… Expand
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Zirconia nanocrystals as submicron level biological label
Inorganic nanocrystals are of increasing interest for their usage in biology and pharmacology research. Our interest was to justify ZrO2 nanocrystal usage as submicron level biological label in… Expand
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Hydrogen‐producing Escherichia coli strains overexpressing lactose permease: FT‐IR analysis of the lactose‐induced stress
The lactose permease gene (lacY) was overexpressed in the septuple knockout mutant of Escherichia coli, previously engineered for hydrogen production from glucose. It was expected that raising the… Expand
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Wood ash and wastewater sludge recycling success in fast- growing deciduous tree - birch and alder plantations
Due to the increasing of wood as energy renewable resource in power and heat plants the amount of wood ash as waste will increase. Wood ash contains plant macronutrient elements P, K and different… Expand
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