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Analysis of myocilin mutations in 1703 glaucoma patients from five different populations.
A glaucoma locus, GLC1A, was identified previously on chromosome 1q. A gene within this locus (encoding the protein myocilin) subsequently was shown to harbor mutations in 2-4% of primary open angleExpand
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Variation in optic nerve and macular structure with age and race with spectral-domain optical coherence tomography.
PURPOSE To evaluate the effects of age and race on optic disc, retinal nerve fiber layer (RNFL), and macular measurements with spectral-domain optical coherence tomography (SD OCT). DESIGNExpand
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Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent.
PURPOSE To perform a quantitative trait locus (QTL) analysis and evaluate whether a locus between SIX1 and SIX6 is associated with retinal nerve fiber layer (RNFL) thickness in individuals ofExpand
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Argon laser trabeculoplasty in pigmentary glaucoma.
PURPOSE To evaluate the long-term effect of argon laser trabeculoplasty (ALT) in pigmentary glaucoma. METHODS The authors retrospectively analyzed results of ALT in 32 eyes of 32 patients withExpand
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Lattice degeneration of the retina and the pigment dispersion syndrome.
Retinal detachment occurs more frequently in patients with pigment dispersion syndrome. We evaluated the incidence of peripheral retinal abnormalities known to predispose to rhegmatogenous retinalExpand
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The effects of race, optic disc area, age, and disease severity on the diagnostic performance of spectral-domain optical coherence tomography.
PURPOSE To evaluate the effect of race (African or European descent), age, disc area, and severity of disease on the diagnostic ability of spectral-domain optical coherence tomography (SDOCT) imagingExpand
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Assessment of Scleral Spur Visibility With Anterior Segment Optical Coherence Tomography
PurposeTo develop a grading system to evaluate the scleral spur visibility and to investigate the association between this and the angle width. MethodsSixty healthy normal subjects (33 with openExpand
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Non-contact in vivo scanning laser microscopy of blebitis
Trabeculectomy with adjunctive antifibrotic agents produces thin, avascular blebs and a greater risk of bleb leakage and infection. These blebs usually demonstrate epithelial breakdown with gobletExpand
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Ultrasound biomicroscopy in pseudophakic malignant glaucoma.
BACKGROUND Malignant glaucoma (ciliary block glaucoma; aqueous misdirection glaucoma) is an incompletely understood, rare and serious complication of intraocular surgery. METHODS A woman withExpand
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Identification and analysis of a novel mutation in the FOXC1 forkhead domain.
PURPOSE To determine the genetic and biochemical defects that underlie Axenfeld-Rieger malformations, identify the pathogenic mutation causing these malformations, and understand how these mutationsExpand
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