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A dysbiosis index to assess microbial changes in fecal samples of dogs with chronic inflammatory enteropathy
- M. Alshawaqfeh, B. Wajid, +5 authors J. Suchodolski
- Biology, Medicine
- FEMS microbiology ecology
- 1 November 2017
qPCR‐based DI was built based on the nearest centroid classifier, and reports the degree of dysbiosis in a single numerical value that measures the closeness in the l2 ‐ norm of the test sample to the mean prototype of each class. Expand
The fecal microbiome and metabolome differs between dogs fed Bones and Raw Food (BARF) diets and dogs fed commercial diets
Investigation of the effect of BARF diets on the fecal microbiome and metabolome found several metabolites were significantly different between diet groups, but lost significance after adjusting for multiple comparison. Expand
Opportunistic Invasive Cutaneous Fungal Infections Associated with Administration of Cyclosporine to Dogs with Immune‐mediated Disease
- B. B. McAtee, K. Cummings, A. Cook, J. Lidbury, J. Heseltine, M. Willard
- Journal of veterinary internal medicine
- 9 September 2017
It is important to consider OIFIs as a potential complication of immunosuppressive treatment, particularly cyclosporine, in dogs diagnosed with certain immune‐mediated diseases and treated with immunOSuppressive drugs. Expand
Variation of the microbiota and metabolome along the canine gastrointestinal tract
The microbiota and metabolome vary significantly at different sites along the canine gastrointestinal tract, including relative concentrations of amino acids which decreased from the small to large intestine; pyruvate, which peaked in the ileum; and several phenol-containing carboxylic acid compounds that increased in the large intestine. Expand
Characterization of the fecal microbiome in cats with inflammatory bowel disease or alimentary small cell lymphoma
Feline chronic enteropathy in cats showed patterns of dysbiosis similar to those in found people with IBD, and no significant difference between the microbiome of cats with I BD and those with SCL was found. Expand
Evaluation of hyaluronic acid, procollagen type III N-terminal peptide, and tissue inhibitor of matrix metalloproteinase-1 as serum markers of canine hepatic fibrosis.
- J. Lidbury, A. R. Hoffmann, J. K. Fry, J. Suchodolski, J. Steiner
- Biology, Medicine
- Canadian journal of veterinary research = Revue…
- 1 October 2016
The utility of measuring serum concentrations of hyaluronic acid, procollagen type III N-terminal peptide, and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) as serum markers of canine hepatic fibrosis is not supported. Expand
Effects of oral versus parenteral cobalamin supplementation on methylmalonic acid and homocysteine concentrations in dogs with chronic enteropathies and low cobalamin concentrations.
Oral and parenteral cobalamin supplementation had the same effect on serum MMA concentrations in this group of dogs, and there was no significant difference between the PO and PE group regarding serum MMA or HCY concentrations at any time point. Expand
The fecal microbiome of dogs with exocrine pancreatic insufficiency.
- Anitha Isaiah, J. C. Parambeth, J. Steiner, J. Lidbury, J. Suchodolski
- Biology, Medicine
- 1 June 2017
It is shown that the fecal microbiome of dogs with EPI (both treated and untreated) is different to that of healthy dogs. Expand
Gastric histopathologic abnormalities in dogs: 67 cases (2002-2007).
Results of this study suggested that intestinal pathologic changes are commonly concurrent in dogs with gastric pathologicChanges, which supports the practice of collecting both gastric and duodenal biopsy specimens every time gastroduodenoscopy is performed. Expand
Fecal Microbial and Metabolic Profiles in Dogs With Acute Diarrhea Receiving Either Fecal Microbiota Transplantation or Oral Metronidazole
- J. Chaitman, Anna-Lena Ziese, +8 authors J. Suchodolski
- Frontiers in Veterinary Science
- 16 April 2020
Fecal consistency improved significantly in dogs treated with FMT and MET by day 7 and day 28, while Dogs treated with MET still had altered microbial and metabolic profiles at day 28 compared to dogs treatedwith FMT or healthy dogs. Expand