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Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
Global energy and environmental problems have stimulated increased efforts towards synthesizing biofuels from renewable resources. Compared to the traditional biofuel, ethanol, higher alcohols offer… Expand
Network component analysis: Reconstruction of regulatory signals in biological systems
- J. Liao, Riccardo Boscolo, Young-Lyeol Yang, Linh M. Tran, C. Sabatti, V. Roychowdhury
- Medicine, Computer Science
- Proceedings of the National Academy of Sciences…
- 12 December 2003
High-dimensional data sets generated by high-throughput technologies, such as DNA microarray, are often the outputs of complex networked systems driven by hidden regulatory signals. Traditional… Expand
Metabolic engineering of Escherichia coli for 1-butanol production.
Compared to ethanol, butanol offers many advantages as a substitute for gasoline because of higher energy content and higher hydrophobicity. Typically, 1-butanol is produced by Clostridium in a… Expand
Driving Forces Enable High-Titer Anaerobic 1-Butanol Synthesis in Escherichia coli
- C. Shen, Ethan I Lan, Yasumasa Dekishima, Antonino Baez, K. M. Cho, J. Liao
- Biology, Medicine
- Applied and Environmental Microbiology
- 11 March 2011
ABSTRACT 1-Butanol, an important chemical feedstock and advanced biofuel, is produced by Clostridium species. Various efforts have been made to transfer the clostridial 1-butanol pathway into other… Expand
The Kármán gait: novel body kinematics of rainbow trout swimming in a vortex street
- J. Liao, D. N. Beal, G. Lauder, M. Triantafyllou
- Medicine, Biology
- Journal of Experimental Biology
- 15 March 2003
SUMMARY Most fishes commonly experience unsteady flows and hydrodynamic perturbations during their lifetime. In this study, we provide evidence that rainbow trout Oncorhynchus mykiss voluntarily… Expand
A review of fish swimming mechanics and behaviour in altered flows
- J. Liao
- Biology, Medicine
- Philosophical Transactions of the Royal Society B…
- 29 November 2007
Fishes suspended in water are subject to the complex nature of three-dimensional flows. Often, these flows are the result of abiotic and biotic sources that alter otherwise uniform flows, which then… Expand
Direct photosynthetic recycling of carbon dioxide to isobutyraldehyde
Global climate change has stimulated efforts to reduce CO2 emissions. One approach to addressing this problem is to recycle CO2 directly into fuels or chemicals using photosynthesis. Here we… Expand
Issues in cDNA microarray analysis: quality filtering, channel normalization, models of variations and assessment of gene effects.
We consider the problem of comparing the gene expression levels of cells grown under two different conditions using cDNA microarray data. We use a quality index, computed from duplicate spots on the… Expand
Metabolic engineering of Escherichia coli for 1-butanol and 1-propanol production via the keto-acid pathways.
Production of higher alcohols via the keto-acid intermediates found in microorganism's native amino-acid pathways has recently shown promising results. In this work, an Escherichia coli strain that… Expand
Metabolic engineering of cyanobacteria for 1-butanol production from carbon dioxide.
Production of chemicals and fuels directly from CO(2) is an attractive approach to solving the energy and environmental problems. 1-Butanol, a chemical feedstock and potential fuel, has been produced… Expand