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Kepler Planet-Detection Mission: Introduction and First Results
Detecting Distant Planets More than 400 planets have been detected outside the solar system, most of which have masses similar to that of the gas giant planet, Jupiter. Borucki et al. (p. 977,Expand
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Characteristics of planetary candidates observed by Kepler, II: Analysis of the first four months of data
On 2011 February 1 the Kepler mission released data for 156,453 stars observed from the beginning of the science observations on 2009 May 2 through September 16. There are 1235 planetary candidatesExpand
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New transiting planet candidates are identified in 16 months (2009 May-2010 September) of data from the Kepler spacecraft. Nearly 5000 periodic transit-like signals are vetted against astrophysicalExpand
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Genomic Analysis of Non-NF2 Meningiomas Reveals Mutations in TRAF7, KLF4, AKT1, and SMO
Genetic Clues to Meningioma Meningiomas are the most common primary brain tumors in adults. Located within the layer of tissue covering the brain, these tumors are usually slow-growing and benign butExpand
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Structure of the CCR5 Chemokine Receptor–HIV Entry Inhibitor Maraviroc Complex
CCR5-Maraviroc Structure The chemokine receptor CCR5, a G protein–coupled receptor best known as a co-receptor during HIV-1 infection, is important in a variety of physiological processes. Tan et al.Expand
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Rapamycin: one drug, many effects.
The mammalian target of rapamycin (mTOR) signaling pathway is a master regulator of cell growth and metabolism. Deregulation of the mTOR pathway has been implicated in a number of human diseases suchExpand
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Microglial activation as a priming event leading to paraquat-induced dopaminergic cell degeneration
Dopaminergic cells in the substantia nigra are highly vulnerable to the neurodegenerative process of Parkinson's disease. Therefore, mechanisms that enhance their susceptibility to injury bearExpand
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Exposure to schistosome eggs protects mice from TNBS-induced colitis.
Crohn's disease results from dysregulated T helper (Th)1-type mucosal inflammation. Crohn's disease is rare in tropical countries but prevalent in developed countries with temperate climates, inExpand
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RNase Z(S1) processes UbL40 mRNAs and controls thermosensitive genic male sterility in rice.
Thermosensitive genic male-sterile (TGMS) lines, which are male-sterile at restrictive (high) temperatures but male-fertile at permissive (low) temperatures, have been widely used in breedingExpand
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The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens.
BACKGROUND A sequenced house dust mite (HDM) genome would advance our understanding of HDM allergens, a common cause of human allergies. OBJECTIVE We sought to produce an annotated DermatophagoidesExpand
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