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Pathogenesis of emerging severe fever with thrombocytopenia syndrome virus in C57/BL6 mouse model
- C. Jin, M. Liang, +21 authors D. Li
- Medicine, Biology
- Proceedings of the National Academy of Sciences
- 4 June 2012
The discovery of an emerging viral disease, severe fever with thrombocytopenia syndrome (SFTS), caused by SFTS virus (SFTSV), has prompted the need to understand pathogenesis of SFTSV. We are unique… Expand
Early diagnosis of novel SFTS bunyavirus infection by quantitative real-time RT-PCR assay.
- Y. Sun, M. Liang, +15 authors D. Li
- Medicine, Biology
- Journal of clinical virology : the official…
BACKGROUND Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease recently identified to be caused by a novel bunyavirus (SFTSV). The clinical diagnosis is urgently… Expand
Severe Fever with Thrombocytopenia Syndrome Virus among Domesticated Animals, China
To investigate the infections of severe fever with thrombocytopenia syndrome virus (SFTSV) in domesticated animals, we sampled a total of 3,039 animals in 2 counties in Shandong Province, People’s… Expand
Epidemic characteristics of hemorrhagic fever with renal syndrome in China, 2006–2012
BackgroundHemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses is a serious public health problem in China. The National Notifiable Disease Surveillance System (NNDSS) was established… Expand
Isolation and phylogenetic characterization of bat astroviruses in southern China
Astroviruses are associated with acute gastroenteritis of human and many animal species. Recently, two studies have reported that novel astroviruses were found in bats. In order to extensively… Expand
Usefulness of the admission shock index for predicting short-term outcomes in patients with ST-segment elevation myocardial infarction.
Current risk scores of ST-segment elevation myocardial infarction (STEMI) need sophisticated algorithm and were limited for bedside use. Our study aimed to evaluate the usefulness of admission shock… Expand
PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5.
PKCζ has emerged as a pathologic mediator of endothelial cell dysfunction, based on its essential role in tumor necrosis factor α (TNFα)-mediated inflammation. In contrast, extracellular… Expand
Influenza A virus‐encoded NS1 virulence factor protein inhibits innate immune response by targeting IKK
The IKK/NF‐κB pathway is an essential signalling process initiated by the cell as a defence against viral infection like influenza virus. This pathway is therefore a prime target for viruses… Expand
Rise and Fall of an Anti-MUC1 Specific Antibody
Background So far, human antibodies with good affinity and specificity for MUC1, a transmembrane protein overexpressed on breast cancers and ovarian carcinomas, and thus a promising target for… Expand
Maternal behavior, pup vocalizations, and pup temperature changes following handling in mice of 2 inbred strains.
- M. Hennessy, J. Li, E. Lowe, S. Levine
- Psychology, Medicine
- Developmental psychobiology
- 1 November 1980
A cross-fostering design was used to examine maternal behavior, pup vocalizations, and pup temperature changes following an infantile procedure in C57BL/6J (C) and A/J (A) mice. In Experiment I,… Expand