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Primer3Plus, an enhanced web interface to Primer3
Here we present Primer3Plus, a new web interface to the popular Primer3 primer design program as an enhanced alternative for the CGI- scripts that come with Primer3. Primer3 consists of a commandExpand
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A text-mining analysis of the human phenome
A number of large-scale efforts are underway to define the relationships between genes and proteins in various species. But, few attempts have been made to systematically classify all suchExpand
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Genealogy of the α-crystallin—small heat-shock protein superfamily
Sequences of 40 very diverse representatives of the α-crystallin–small heat-shock protein (α-Hsp) superfamily are compared. Their characteristic C-terminal `α-crystallin domain' of 80–100 residuesExpand
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QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyploid species
BackgroundSingle nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use of the large numberExpand
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The quest for orthologs: finding the corresponding gene across genomes.
Orthology is a key evolutionary concept in many areas of genomic research. It provides a framework for subjects as diverse as the evolution of genomes, gene functions, cellular networks andExpand
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The expanding small heat-shock protein family, and structure predictions of the conserved “α-crystallin domain”
The ever-increasing number of proteins identified as belonging to the family of small heat-shock proteins (shsps) and α-crystallins enables us to reassess the phylogeny of this ubiquitous proteinExpand
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The human genome encodes 10 α-crystallin–related small heat shock proteins: HspB1–10
Abstract To obtain an inventory of all human genes that code for α-crystallin–related small heat shock proteins (sHsps), the databases available from the public International Human Genome SequencingExpand
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The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10.
To obtain an inventory of all human genes that code for alpha-crystallin-related small heat shock proteins (sHsps), the databases available from the public International Human Genome SequencingExpand
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MADMAX - Management and analysis database for multiple ~omics experiments
The rapid increase of ~omics datasets generated by microarray, mass spectrometry and next generation sequencing technologies requires an integrated platform that can combine results from differentExpand
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A Protein Classification Benchmark collection for machine learning
Protein classification by machine learning algorithms is now widely used in structural and functional annotation of proteins. The Protein Classification Benchmark collection () was created in orderExpand
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  • Open Access