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Molecular Spectra and Molecular Structure
THOSE who contributed to the recent Faraday Discussion on molecular spectra and molecular structure have now sent their written versions to the secretary for publication. Instead of the report we…
View on Nature
Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD).
TLDR
The higher overall incidence rates in northern centres did not seem to be explained by differences in tobacco consumption or education, and the magnitude of the observed excess for both conditions is less than expected on the basis of previous studies.
View on BMJ
Classification of inflammatory bowel disease.
Infection, ischaemia, physical damage, or specific immunologic sensitivity should be excluded as far as possible before a diagnosis of non-specific inflammatory bowel disease is made. Non-specific…
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Mapping of a susceptibility locus for Crohn's disease on chromosome 16
TLDR
A genome-wide search performed on two consecutive and independent panels of families with multiple affected members, using a non-parametric two-point sibling-pair linkage method, identified a putative CD-susceptibility locus on chromosome 16 which contains candidate genes which may be relevant to the pathogenic mechanism of inflammatory bowel diseases.
View on Nature
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
View on Elsevier
Factors affecting the outcome of endoscopic surveillance for cancer in ulcerative colitis.
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Long-term neoplasia risk after azathioprine treatment in inflammatory bowel disease
View on Elsevier
Bone marrow toxicity caused by azathioprine in inflammatory bowel disease: 27 years of experience.
TLDR
The blood count has been reviewed in all patients treated with azathioprine for inflammatory bowel disease over 27 years in one hospital and leucopenia is the commonest and most important haematological complication.
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Randomised controlled trial of azathioprine withdrawal in ulcerative colitis.
TLDR
Demonstration of the relapse preventing properties of azathioprine has implications for a large number of patients with troublesome ulcerative colitis, who may benefit from treatment with azathyprine.
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A genomewide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort.
TLDR
This genomewide linkage scan, done with a large family cohort, has confirmed three previous IBD linkages and has provided evidence for five additional regions that may harbor IBD predisposition genes.
View on PubMed
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