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Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs.
- J. Lee, Dong-soon Lee, +6 authors S. Lee
- American journal of respiratory and critical care…
- 15 October 2005
RATIONALE In cigarette smoking-induced chronic obstructive pulmonary disease, structural and functional derangements are characterized by parenchymal destruction and pulmonary hypertension. Statins… Expand
Evaluation of the fate of perfluoroalkyl compounds in wastewater treatment plants.
Recent studies have shown that the wastewater treatment plant (WWTP) is a significant source of perfluoroalkyl compounds (PFCs) in natural water. In this study, 10 PFCs were analyzed in influent and… Expand
Characteristics of indoor and outdoor bioaerosols at Korean high-rise apartment buildings.
This study attempted to evaluate the bioaerosol exposure of apartment residents at high-rise apartment buildings in a Korean city. The characteristics associated with the bioaerosol exposure included… Expand
Optimization of conditions for the production of pullulan and high molecular weight pullulan by Aureobasidium pullulans
Aureobasidium pullulans had a maximum yield coefficient of pullulan (Yp/s=0.24) with an initial pH of the culture broth of 6.5 in a shake-flask culture. In a batch culture, the maximum pullulan yield… Expand
Antitumor activity of Pulsatilla koreana saponins and their structure-activity relationship.
- S. Bang, J. Lee, G. Song, D. Kim, M. Yoon, B. Ahn
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 1 November 2005
Seventeen saponins isolated from the root of Pulsatilla koreana were examined for their in vitro cytotoxic activity against the human solid cancer cell lines, A-549, SK-OV-3, SK-MEL-2, and HCT15,… Expand
Responses to inhaled long-acting beta-agonist and corticosteroid according to COPD subtype.
RATIONALE Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disorder in which a number of different pathological processes lead to recognition of patient subgroups that may… Expand
Targeted sequencing identifies genetic alterations that confer primary resistance to EGFR tyrosine kinase inhibitor (Korean Lung Cancer Consortium)
Background Non-small-cell lung cancer (NSCLC) patients with activating epidermal growth factor receptor (EGFR) mutations may exhibit primary resistance to EGFR tyrosine kinase inhibitor (TKI). We… Expand
Airborne Fungal and Bacterial Levels Associated With the Use of Automobile Air Conditioners or Heaters, Room Air Conditioners, and Humidifiers
- Wan-Kuen Jo, J. Lee
- Environmental Science, Medicine
- Archives of environmental & occupational health
- 1 September 2008
The authors performed 3 experiments to measure temporal variation in airborne bacterial and fungal levels associated with the use of air conditioners (ACs), heaters, and humidifiers. The… Expand
Inhaled corticosteroid is associated with an increased risk of TB in patients with COPD.
BACKGROUND It is well known that oral corticosteroid and anti-tumor necrosis factor-α agents increase the risk of TB. However, little is known about whether inhaled corticosteroid (ICS) increases the… Expand
Purification and characterization of ginsenoside Ra-hydrolyzing beta-D-xylosidase from Bifidobacterium breve K-110, a human intestinal anaerobic bacterium.
- Hoyoung Shin, J. Lee, J. Lee, Yeo-Ock Han, M. Han, D. Kim
- Biology, Medicine
- Biological & pharmaceutical bulletin
- 1 August 2003
Beta-D-Xylosidase (EC 188.8.131.52) has been purified from ginsenoside Ra-metabolizing Bifidobacterium breve K-110, which was isolated from human intestinal microflora. beta-D-Xylosidase was purified to… Expand