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Development of a closed-system process for clinical-scale generation of DCs: evaluation of two monocyte-enrichment methods and two culture containers.
Together, the Isolex system and Stericell bags can be incorporated into a closed-system process to generate immature DCs in either flasks or bags. Expand
Development of a clinical-scale method for generation of dendritic cells from PBMC for use in cancer immunotherapy.
This goal was to develop a clinical scale method to prepare autologous DCs for cancer clinical trials that avoids the use of FBS and results in immature DCs suitable for clinical trials. Expand