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Controlling Long-Range Genomic Interactions at a Native Locus by Targeted Tethering of a Looping Factor
Chromatin loops juxtapose distal enhancers with active promoters, but their molecular architecture and relationship with transcription remain unclear. In erythroid cells, the locus control region… Expand
The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation.
The β-globin locus control region (LCR) is necessary for high-level β-globin gene transcription and differentiation-dependent relocation of the β-globin locus from the nuclear periphery to the… Expand
Robust Speaker Recognition Against Utterance Variations
A speaker model in speaker recognition system is to be trained from a large data set gathered in multiple sessions. Large data set requires large amount of memory and computation, and moreover it's… Expand
Fetal γ-globin genes are regulated by the BGLT3 long noncoding RNA locus.
- Maria Soledad Ivaldi, Luis Francisco Diaz, L. Chakalova, J. Lee, I. Krivega, A. Dean
- 1 November 2018
Long noncoding RNAs (lncRNAs) are increasingly being appreciated as participants in regulation of important cellular processes, including transcription. Because lncRNAs are highly cell type specific,… Expand
Closed-Form Expressions for the Noise Voltage Caused by a Burst Train of IC Switching Currents on a Power Distribution Network
A burst stimulus of data is a common activity in circuits and systems. The supply noise voltage waveform induced by a burst train of integrated circuit (IC) switching currents is rigorously derived… Expand
Suppression of coupled-slotline mode on CPW using air-bridges measured by picosecond photoconductive sampling
For the first time, the effect of air-bridges on the suppression of the unwanted coupled-slotline (CSL) mode on a coplanar waveguide (CPW) is experimentally observed up to 250-GHz bandwidth, based on… Expand
Distinct Ldb1/NLI complexes orchestrate γ-globin repression and reactivation through ETO2 in human adult erythroid cells.
The Ldb1/GATA-1/TAL1/LMO2 complex mediates long-range interaction between the β-globin locus control region (LCR) and gene in adult mouse erythroid cells, but whether this complex mediates chromatin… Expand
Quantification of lurasidone, an atypical antipsychotic drug, in rat plasma with high-performance liquid chromatography with tandem mass spectrometry.
- Tae-sung Koo, Soo-Jin Kim, JongJoo Lee, Dong-Jin Ha, Myoungki Baek, Hongsik Moon
- Chemistry, Medicine
- Biomedical chromatography : BMC
- 1 December 2011
A liquid chromatography-tandem mass spectrometric (LC/MS/MS) method was developed for the determination of an atypical antipsychotic drug, lurasidone, in rat plasma. The method involves the addition… Expand
An Enhanced Statistical Analysis Method for I/O Links Considering Supply Voltage Fluctuations and Intersymbol Interference
- J. Kim, J. Lee, E. Park, Youngwoo Park
- IEEE Transactions on Components, Packaging and…
- 30 July 2015
Statistical link analysis methods were previously developed for effective computation of bit error rate due to intersymbol interference (ISI). In addition to ISI, supply voltage fluctuations at… Expand
The LDB1 complex co-opts CTCF for erythroid lineage specific long-range enhancer interactions
Lineage-specific transcription factors are critical for long-range enhancer interactions but direct or indirect contributions of architectural proteins such as CTCF to enhancer function remain less… Expand